PREVALENCE AND ANTIBIOTIC SUSCEPTIBILITY PATTERN OF PSEUDOMONAS AERUGINOSA ISOLATES FROM WOUND INFECTIONS

N. Aby Chandy, Dr Kalyani M

Abstract


INTRODUCTION: Wound infections are the most common sources of morbidity worldwide. According to
recent studies conducted it has come to light that various wound infectons are caused by Pseeudomonas
aeruginosa than Staphylococcus aureus. Pseudomonas aeruginosa is one of the most important microorganisms
that cause clinical problems resulting from high resistance to antimicrobial agents. Therefore the present
study was undertaken to find out the antibiotic susceptibility patterns of P.aeruginosa from various specimens
of wound infections.
AIM AND OBJECTIVES: To detect the prevalence and antibiotic susceptibility pattern of Pseudomonas
aeruginosa isolates from wound infections.
MATERIALS AND METHODS: A total of 100 samples were collected from both male and female patients of all
ages of both IP and OP patients attending Saveetha Medical college and hospital Thandalam Chennai. Swabs
were taken from wounds by the use of swab sticks and scalpel blades. The antibiotic disc used were Amikacin,
Gentamicin, Amoxycillin, Tetracycline, Ampicillin and Ofloxacin. The results were interpreted as sensitive or
resistant based on CLSI guidelines.
RESULTS: In our study on antibiotic susceptibility pattern of P.aeruginosa isolates the percentage of resistant
strains 51% and 35.5% respectively against gentamicin and amikacin. In our study the most number of strains
were susceptible to ofloxacin(75.5%), gentamycin(58.5%), ceftriazone(56.3%) which could be used as reserve
drugs in case of severe illiness due to pseudomonas infection.
CONCLUSION: The result of this research showed that Pseudomonas aeruginosa was the most frequent pathogen
isolated accounting for the total no of cases seen in Saveetha medical college. The susceptibility profile of P.aeruginosa
isolates to the ten antimicrobials tested in vitrowere relatively low compared to the sensitivity pattern to different
antipseudomonal drugs reported worldwide.


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