STUDY OF CHANGES IN LUNG FUNCTION TEST IN PREGNANCY
Abstract
Background: Pregnancy is characterized by various physiological changes that have an impact on multiple organ system functions and associated with various changes in pulmonary anatomy and physiology to accommodate the needs of the developing fetus. These changes in lung parameters can be assessed by spirometry, a simple, inexpensive and effective method.
Aim: To assess the changes in lung function in 1st, 2nd & 3rd trimesters during normal pregnancy.
Methods: The study consisted of recording the pulmonary function tests in 160 female volunteers divided into four groups (each group having about 40 females) including pregnant women of various phases of gestational period 12 weeks, 24 weeks, 36 weeks in the age group of 20-35 years either primigravida or multigravida with haemoglobin count more than 10 gm% from antenatal OPD GMCH, Chandrapur. The age matched controls were the volunteers from the relatives of pregnant women who attended the OPD and from amongst the hospital staff and students. FVC, FEV1, PEFR, FEF 25-75%, MVV and ERV were recorded in all volunteers by using Spiroexcel digital spirometer, Medicaid systems. Results were expressed as mean ± S.D. and compared with Student’s t test.
Results and Conclusion: As compared with controls, there is significant decrease in lung parameters namely, FVC, FEV1, PEFR, FEF 25-75%, MVV and ERV progressively in all the trimesters of normal pregnancy.
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