Dr Prathap R, Dr Asim P A, Dr Midun Mohandas


Introduction: Chronic Suppurative Otitis Media (CSOM) is a potentially serious disease because of its complications. The incidence of CSOM is increasing in the developing countries because of the poor hygiene practices and lack of health education.

Pseudomonas aeruginosa is a Gram-negative bacterium belonging to the family Pseudomonadaceae that is able to survive in a wide range of environments.

 Aim: To determine the microbiological profile and antimicrobial sensitivity pattern of Pseudomonas aeruginosa from discharge in CSOM.

Material and method: This study was conducted over a time period of 6 months. All bacterial isolates were identified by conventional microbiological methods. Antimicrobial sensitivity testing of the isolates was done by Kirby-Bauer disc diffusion method according to Clinical and Laboratory Standards Institute (CLSI) guidelines.

Result: Pseudomonas aeruginosa (58.6 %) was the most prevalent bacteria isolated, followed by staphylococcus aureus (19.57%).Most sensitive antibiotic against Pseudomonas aeruginosa was Piperacillin – Tazobactum (76.5%) followed by Meropenam (65.8%) and cephalosporins such as cephalexin, cefuroxime. Amoxyllin-clavulanic acid shows complete resistance towards Pseudomonas aeruginosa.

Conclusion: It is important to evaluate bacteriologic profile and antimicrobial susceptibility pattern periodically for efficacious treatment in CSOM patients


Chronic Suppurative Otitis Media (CSOM), Pseudomonas aeruginosa, MICROBIOLOGICAL

Full Text:



Dr. Nawaz Umar, Bilal Ahmad Mir. Prevalence and antibiogram of Pseudomonas aeruginosa isolated from otitis media in KBN hospital, Gulbarga. Sch J App Med Sci 2015;3(7A):2502-2505.

Silby MW, Winstanley C, Godfrey SA, Levy SB, Jackson RW. Pseudomonas genomes: diverse and adaptable. FEMS Microbiol Rev 2011;35:652–680.

Breidenstein EB, de la Fuente-Nunez C, Hancock RE. Pseudomonas aeruginosa: all roads lead to resistance. Trends Microbiol 2011;19:419–426.

Drenkard E. Antimicrobial resistance of Pseudomonas aeruginosa biofilms. Microbes Infect 2003;5:1213–1219.

Swapnil R. Pawar, Yogesh Shukla. A clinical study on complications of chronic suppurative otitis media and level of awareness in patients admitted at tertiary care hospital in central India. Int J Community Med Public Health 2015;2(3):223-227.

Shyamala R, Reddy PS. The study of bacteriological agents of chronic suppurative otitis media--aerobic culture and evaluation. J Microbiol Biotechnol Res 2017;2:152–62.

. Poorey VK, Iyer A; Study of bacterial flora in CSOM and its clinical significance. Indian J Otolaryngol Head Neck Surg 2002;54(2):91-95.

Prakash M, Lakshmi K, Anuradha S, Swathi GN. Bacteriological profile and their antibiotic susceptibility pattern of cases of Chronic Suppurative Otitis Media. Asian J Pharma Clin Res 2013;6(3):210-212.

Mansoor T, Musani MA, Khalid G, Kamal M. Pseudomonas aeruginosa in chronic suppurative otitis media: Sensitivity spectrum against various antibiotics in Karachi. J Ayub Med Coll Abbottabad 2009;21(2):120- 123.

Wadile Rahul Gopichand, Bhate Viraj Madhusudan and Kalshetti Varsha Tukaram. Bacteriological Profile of Chronic Suppurative Otitis Media. Int J Curr Microbiol App Sci 2015;4(6):41-47.

Bairy I, Pradhan D, Yenigalla BM. Microbiology of chronic suppurative otitis media. lnt J Otol 2007;13:21-4.

Maji PK, Chatterjee TK, Chatterjee S, et al. The investigation of bacteriology of chronic suppurative otitis media in patients attending a tertiary care hospital with special emphasis on seasonal variation. Ind J Otolaryngol Head Neck Surg 2007;59(2):128-31.

Kumar S, Sharma R, Saxena AK, et al. A study of bacterial flora and sensitivity to antibiotics in cases of CSOM TTD in western UP. Ind J Otol 2016;14:20-4.

Indudharan R, Haq JA, Aiyar S. Antibiotics in chronic suppurative otitis media: a bacteriologic study. Ann Otol Rhinol Laryngol 1999;108(5):440-5

Rakesh kumar, P. srivastava, M. sharma, S. Rishi, PS. Nirwan, K. Hemwani, SS. Dahiya. Isolation of antimicrobial sensitivity profile of bacterial agents in chronic suppurative otitis media patients at NIMS hospital, Jaipur. IJPBS 2013;3(4):265-269.

Kumar Ajay, Kumari Namrata, Kumar Shailesh, Kumar Rakesh, Xess Anima, Shahi SK. Prevalence and antimicrobial sensitivity pattern of Pseudomonas aeruginosa from chronic suppurative otitis media (CSOM) cases in a tertiary care hospital of Bihar. J Evol Med Dent Sci 2017;6:70.

Mansoor T, Musani MA, Khalid G, Kamal M. Pseudomonas aeruginosa in chronicsupperative otitis media: sensitivity spectrum against various antibiotics in Karachi. J Ayub Med coll Aottaabad 2009;21(2):120-23.


  • There are currently no refbacks.