PSEUDOMONAS AERUGINOSA; MICROBIOLOGICAL PROFILE AND ANTIMICROBIAL SENSITIVITY PATTERN IN CHRONIC SUPPURATIVE OTITIS MEDIA

Dr Prathap R, Dr Asim P A, Dr Midun Mohandas

Abstract


Introduction: Chronic Suppurative Otitis Media (CSOM) is a potentially serious disease because of its complications. The incidence of CSOM is increasing in the developing countries because of the poor hygiene practices and lack of health education.

Pseudomonas aeruginosa is a Gram-negative bacterium belonging to the family Pseudomonadaceae that is able to survive in a wide range of environments.

 Aim: To determine the microbiological profile and antimicrobial sensitivity pattern of Pseudomonas aeruginosa from discharge in CSOM.

Material and method: This study was conducted over a time period of 6 months. All bacterial isolates were identified by conventional microbiological methods. Antimicrobial sensitivity testing of the isolates was done by Kirby-Bauer disc diffusion method according to Clinical and Laboratory Standards Institute (CLSI) guidelines.

Result: Pseudomonas aeruginosa (58.6 %) was the most prevalent bacteria isolated, followed by staphylococcus aureus (19.57%).Most sensitive antibiotic against Pseudomonas aeruginosa was Piperacillin – Tazobactum (76.5%) followed by Meropenam (65.8%) and cephalosporins such as cephalexin, cefuroxime. Amoxyllin-clavulanic acid shows complete resistance towards Pseudomonas aeruginosa.

Conclusion: It is important to evaluate bacteriologic profile and antimicrobial susceptibility pattern periodically for efficacious treatment in CSOM patients


Keywords


Chronic Suppurative Otitis Media (CSOM), Pseudomonas aeruginosa, MICROBIOLOGICAL

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References


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