ANAL CANAL MELANOMA MASQUERADING AS HEMORRHOIDS

S. P Gayathre, M. Kudiyarasu, R. Kannan, Manasa A

Abstract


Primary malignant melanoma of anus is a rare and an aggressive neoplasm that tends to invade locally and metastasize early in the course of the disease. It is often misdiagnosed as hemorrhoids or as one of the benign anorectal disorders, due to the lack of pathognomonic symptoms. Owing to the aggressive nature and delayed diagnosis, the prognosis remains dismal, being less than 20%. Optimal treatment is still controversial with no significant survival advantage and ranges from a less morbid wide local excision to a significantly morbid Abdomino perineal resection. Chemotherapy or radiotherapy are kept in store for more advanced disease. We report a case of a 38 year old male with a mass descending per rectum, misdiagnosed as hemorrhoids and later proved to be advanced malignant melanoma of anal canal.


Keywords


primary anal melanoma, hemorrhoids, abdominoperineal resection

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References


Singer M, Mutch M G: Anal melanoma. Clin Colon Rectal Surg 2006;19:78-87

Chute DJ, Cousar JB, Millis SE: Anorectal malignant melanoma: morphological and immunohistochemical features. Am J Clin Pathol 2006 ;126:93-100

Moore R: Recurrent melanosis of the Rectum, after previous removal the verge of anus, in a man aged sixty-five. Lancet 1857;1:290

Kelly P, Zagers GK, Cormier JN, Ross MI: Sphicter sparing local excision and hypofractionated radiation therapy for anorectal melanoma: a 20 year experience . Cancer 2011; 117:4747-4755

Kim KB, Sanguino AM , Hodges G et all, : Biochemotherapy in patients with metastatic anorectal mucosal melanoma . Cancer 2004;100:1478-1483

Chang AE, Karnell LH, Meneck HR: the cancer datebase report on cutaneous and non-cutaneous melanoma : a summary of 84, 836 cases from the past decade . The Americans College of Surgeons Commision on Cancer and American Cancer Society. Cancer 1998;83:1664-1678

Zhang S, Gao F, Wan D: Effect of misdiagnosis on the prognosis of anorectal malignant melanoma. J Cancer Res Clin Oncol 2010;136:1401-1405

Morson BC, Volkstadt H: Malignant melanoma of the anal canal .J Clin Pathol 1963;16:126-132

Slinglugg CL Jr, Seigler HF: Anorectal Melanoma : clinical characteristics and the role of abdominoperineal resection. Ann plast Surg 1992;28:85-88

DeMatos P, Tyler DS, Seigler HF: Malignant melanoma of the mucous membranes : a review of 119 cases. Ann Surg Oncol 1998;5:733-742


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