ORBITAL AND NASAL COMPLICATIONS OF FUNGAL SINUSITIS IN A IMMUNOCOMPROMISED PATIENT

Dr. Sridhara Narayanan, Dr. M. K. Rajasekar, Dr. S. Shaheera Tarnoom

Abstract


Despite availability of excellent antibiotics, orbital and nasal complications following sinusitis is rather common. Prevalence of life style disorders
like diabetes mellitus has added to the woes. This article attempts to emphasize the role of Otorhinolaryngologist in early recognition and treating
the three diseases such as fungal sinusitis/septal abscess/3rd nerve palsy in a patient with uncontrolled diabtes mellitus.


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References


Aleksic M, Walcher D, Giehl K, Bach H, Grub M, Durst R, et al. Signalling processes involved in C-peptide-induced chemotaxis of CD4 positive lymphocytes. Cell Mol Life Sci. 2009;66(11-12):1974–1984.

Al-Rasheed NM, Chana RS, Baines RJ, Willars GB, Brunskill NJ, et al. Ligand independent activation of peroxisome proliferator-activated receptor-gamma by insulin and C-peptide in kidney proximal tubular cells: dependent on phosphatidylinositol 3-kinase activity. J Biol Chem. 2004;279(48):49747-54.

Rye KA, Barter PJ. Cardioprotective functions of HDLs. J Lipid Res. 2014;55(2):168-79.

Patel N, Taveira TH, Choudhary G, Whitlatch H, Wu WC. Fasting serum C-peptide levels predict cardiovascular and overall death in nondiabetic adults. J Am Heart Assoc. 2012;1(6):e003152.

Khan SS, Ning H, Wilkins JT, Allen N, Carnethon M, Berry JD, et al. Association of Body Mass Index with Lifetime Risk of Cardiovascular Disease and Compression of Morbidity. JAMA Cardiol. 2018;3(4):280-287.

Reaven GM. Insulin resistance, the insulin resistance syndrome, and cardiovascular disease. Panminerva Med. 2005;47(4):201-210.

Heitzer T, Schlinzig T, Krohn K, Meinertz T, Münzel T. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation. 2001;104(22):2673-2678.

Higashi Y, Sasaki S, Nakagawa K, Matsuura H, Oshima T, Chayama K, et al. Endothelial function and oxidative stress in renovascular hypertension. N Engl J Med. 2002;346:1954-1962.

Marx N, Walcher D, Raichle C, Aleksic M, Bach H, Grub M, et al. C-peptide colocalizes with macrophages in early arteriosclerotic lesions of diabetic subjects and induces monocyte chemotaxis in vitro. Arteriosclerosis, thrombosis and vascular biology. 2004;24(3):540-545.

Walcher D, Aleksic M, Jerg V, HombachV,Zieske A, Homma S,et al. C-peptide induces chemotaxis of human CD4 positive cells: involvement of pertussis toxin sensitive G-proteins and phosphoinositide 3-kinase. Diabetes. 2004;53(7):1664-1670.


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