ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF ENTEROCOCCUS SPECIES ISOLATED FROM URINE SAMPLES FROM A TERTIARY CARE HOSPITAL
Abstract
Enterococcus species have emerged as very important pathogens causing urinary tract infections and multi drug resistance among Enterococci further add to the problem. A total of 105 Enterococci were isolated from urine samples. Speciation was done according to Facklams and Collins conventional method. Antimicrobial susceptibility pattern was determined by Kirby Bauer disc diffusion method. Among 105 Enterococcal isolates, E. faecium was predominant species 71(67.62%) over E. faecalis 34(32.38%). There was alarmingly high resistance to commonly used antimicrobial agents including quinolones (88-93%), ampicillin(71.4%) and high level gentamicin(62.8%). E. faecium was found to be more resistant than E. faecalis (p <0.05).Considering increasing isolation of multi drug resistant Enterococci from urine samples there is a need to carry-out regular surveillance of antimicrobial resistance of Enterococci to recommend appropriate therapy.
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Bourdon N1, Fines-Guyon M, Thiolet JM, Maugat S, Coignard B, Leclercq R, Cattoir V. Changing trends in vancomycin-resistant enterococci in French hospitals. 2011;66(4):713-21
Ali S, Mirza IA, Yaqoob S, Hussain A, Khan I, Rafiq MY. Antimicrobial susceptibility pattern of Enterococcus species isolated from patients with urinary tract infection. Gomal J Med Sci 2014;12:11-4.
Kristich C, Wells C and Dunny G.A eukaryotic-type Ser/Thr kinase inEnterococcus faecalismediates antimicrobial resistance and intestinal persistence. Pnas. 2007;104(9):3508-3513
Fraser L, Brusch L. 17/03/2016. Drugs & Diseases-Infectious Diseases Enterococcal Infections.
Bose M, Chatterjee S S, Mukherjee K, Das S, Ghosh C, Chakraborty B, ChaterjeeM,et al.Enterococcal urinary tract infection. an emerging threat. Journal of Evolution of Medical and Dental Sciences. 2015;4(17):2898-2904. DOI: 10.14260/jemds/2015/419
Saraswathy MP. Multidrug resistant Enterococci isolated from urine samples at a tertiary care hospital.Indian J Microbiol Res 2015;2(4):214-219
Mark M. Huycke, Daniel F. Sahm, and Michael S. Gilmore.Synopsis Multiple-Drug Resistant Enterococci: The Nature of the Problem and an Agenda for the Future.1998;4(2)
Treatment of Resistant Enterococcal Urinary Tract Infections. Current Infectious Disease Reports 2010;12(6):455–464.
Koneman EW, Allen SD, Janda WM, Schreckenberger PC, Winn WC Jr. The gram positive cocci. Part II: Streptococci, Enterococci and the Streptococcus-like bacteria. In Koneman’s Color Atlas and Textbook of Diagnostic Microbiology. 5th Ed.
Ross PW. Streptococci and Enterococci. Mackie and Mccartney’s Practical Medical Microbiology, 14th edition. Elsievier, 2013;268-69.
Forbes BA,Sahm DF, Weissfeld AS. Overview of Bacterial Identification Methods and Strategies. Bailey and Scott ‘s Diagnostic Microbiology,12th edition. Mosby, 2007;216-47.
Facklam RR. Recognition of the Group D Streptococcal species of human origin by doing biochemical and physiological tests. J Appl Microbiol 1972;23(6):1131-39.
CLSI. Performance Standards for Antimicrobial Susceptibility Testing. 28th ed. CLSI supplement M100. Wayne, PA: Clinical and Laboratory Standards Institute; 2018.
Ali S, Mirza IA, Yaqoob S, Hussain A, Khan I, Rafiq MY. Antimicrobial susceptibility pattern of Enterococcus species isolated from patients with urinary tract infection. Gomal J Med Sci 2014;12:11-4.
Saraswathy MP. Multidrug resistant Enterococci isolated from urine samples at a tertiary care hospital. Indian J Microbiol Res 2015;2(4):214-219
Parameswarappa J, Basavaraj VP, Basavaraj CM. Isolation, identification, and antibiogram of Enterococci isolated from patients with urinary tract infection. Ann Afr Med.2013;12:176-81.
Naik BT, Lavanya J, Mane V, Upadhya KA.Enterococci speciation and antibiogram: an assessment of data at a tertiary care hospital in Karnataka. Indian J Microbiol Res 2016;3(2):130-135
Akther J, Ahmed S, Anwar A. Antimicrobial Susceptibility Patterns of Enterococcus species Isolated from Urinary Specimens. Bangladesh Journal of Medical Microbiology 2014; 08(01):16-20.
Kanthishree B. Haritsa, Shashikala N, Sunil Kumar D. Chavan, Sangeetha S. “Isolation, Identification and Speciation of Enterococci and their Antimicrobial Susceptibility in a Tertiary Care Hospital”. Journal of Evolution of Medical and Dental Sciences 2014;3(63):13893-13899 DOI: 10.14260/jemds/2014/3857
Goel V, Kumar D, Kumar R, Mathur P, Singh S. Community acquired enterococcal urinary tract infections and antibiotic resistance profile in North India. J Lab Physicians 2016;8:50-4.
Karmarkar MG, Gershom ES and Mehta PR. Enterococcal infections with special reference to phenotypic characterization & drug resistance. Indian J Med Res. 2004;119:22-25
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