Mithun Reddy CH, Armel Arputha Sivarajan A, Raju MVS


                   Cirrhosis is the common endpoint of chronic liver disease affecting more than one third of the population all over the world causing significant morbidity and mortality. Complications of cirrhosis include portal hypertension, esophageal varices, variceal bleeding, ascites. Till date screening upper GI endoscopy is used as a prophylactic measure in all cirrhotic patients which also helps in choosing the treatment option that the patient should undergo. However in view of its inherent invasive complications sonoelastography has come in to picture for measuring spleen stiffness which would act as a radiological parameter for early detection of complications associated with chronic liver disease. The aim was to undertake a review about the significance of spleen stiffness measurement as a radiological predictor in chronic liver disease patients. A literature search was conducted using Pub Med and Google Scholar up to January 2020 with the following key words “spleen stiffness”, “ARFI”, “ARFI in spleen stiffness” and “ARFI in cirrhotic liver disease”. A total of 14 studies met the inclusion criteria and were included in the analysis. Based on the results of the study, it can be concluded that spleen stiffness using acoustic radiation force impulse imaging can act as a early radiological predictor for detection of complications associated with chronic liver disease patients.


Elastography , Spleen stiffness , Arfi ,Chronic liver disease.

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