EFFECT OF SEROTONIN ON MOOD CHANGES IN FIRST YEAR MEDICAL STUDENTS.
Abstract
Mood is the behavioral and emotional state of mind. It is documented that serotonin is neurotransmitter plays a pivotal role in mood regulation and has image feelings of well-being and happiness been studied as mood changer during various responses. The present study was performed to evaluate the relationship between serotonin levels and mood changes among first year medical students. The study revealed that a relationship does indeed exist between serotonin levels and various responses related to mood change and overall feeling of well being. This study hopes that further clinical implications may be done in cases of mood changes and mood disorders by monitoring and treating serotonin deficiency in these patients.
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Hensler, J. G., Kovachich, G. B., & Frazer, A. (1991). A quantitative autoradiographic study of serotonin1A receptor regulation: Effect of 5,7-dihydroxytryptamine and antidepressant treatments. Neuropsychopharmacology, 4(2), 131–144.
Twarog Bm, Page Ih. (1953): Serotonin Content Of Some Mammalian Tissues And Urine And A Method For Its Determination. Am J Physiol 175: 157–161
Cassel, J.C. (2010). Experimental Studies on the Role(s) of Serotonin in Learning and Memory Functions. In: Handbook of the Behavioral Neurobiology of Serotonin, Vol. 21. C.P. M u ller and B.L. Jacobs, eds. (Amsterdam: Academic Press), pp. 429 – 447.
Friedman M., Levin C.E. Nutritional and medicinal aspects of d-amino acids. Amino Acids. 2012;42:1553–1582. doi: 10.1007/s00726-011-0915-1. [PubMed] [CrossRef] [Google Scholar]
Herrera C.P., Smith K., Atkinson F., Ruell P., Chow C.M., O’Connor H., Brand-Miller J. High-glycaemic index and -glycaemic load meals increase the availability of tryptophan in healthy volunteers. Br. J. Nutr. 2011;105:1601–1606. Doi,10.1017/S0007114510005192. [PubMed] [CrossRef] [Google Scholar]
Young V.R., Hussein M.A., Murray E., Scrimshaw N.S. Plasma tryptophan response curve and its relation to tryptophan requirements in young adult men. J. Nutr. 1971;101:45–59. [PubMed] [Google Scholar]
Richard D.M., Dawes M.A., Mathias C.W., Acheson A., Hill-Kapturczak N., Dougherty D.M. L-tryptophan: Basic metabolic functions, behavioral research and therapeutic indications. Int. J. Tryptophan Res. IJTR. 2009;2:45–60.
Young SN, Gauthier S, Anderson GM, Purdy WC. Tryptophan, 5-hydroxyindoleacetic acid and indoleacetic acid in human cerebrospinal fluid: interrelationships and the influence of age, sex, epilepsy and anticonvulsant drugs. J Neurol Neurosurg Psychiatry. 1980 May;43(5):438–445.
S. Nishizawa, C. Benkelfat, S. N. Young, M. Leyton, S. Mzengeza, C. de Montigny, P. Blier, and M. Diksic,. Differences between males and females in rates of serotonin synthesis in human brain.
H.G.Baumgarten, M Gothert. Serotoninergic Neuron and 5 HT Receptors in the CNS edition 1997.
Giuseppe Di Giovanni, Vincenzo Di Matteo and Ennio Esposito, Serotonin Dopamine interaction, experimental evidence and therapeutic relevance. Vol 172.
Julie G Hensler, Regulation of 5 HT1A receptor function in brain following agonist or antidepressant administration. Vol. 72 issue 15, Feb 2003, Pages 1665 – 1682.
Julie G Hensler, Differential Regulation of 5-HT1A Receptor-G Protein Interactions in Brain Following Chronic Antidepressant Administration, Neuropsychopharmacology, Volume 26, Issue 5, May 2002, Pages 565-573.
Hensler, J. G., Kovachich, G. B., & Frazer, A. (1991). A quantitative autoradiographic study of serotonin1A receptor regulation: Effect of 5,7-dihydroxytryptamine and antidepressant treatments. Neuropsychopharmacology, 4(2), 131–144.
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