CANDIDA SPECIATION AND ANTIFUNGAL SUSCEPTIBILITY PATTERN FROM CLINICAL SAMPLES IN A TERTIARY CARE CENTRE.

Sapna Malik, Vidya Shetty, Jyothirlatha Bangera

Abstract


Introduction: Candida can cause life threatening invasive to non life threatening mucocutaneous diseases. It is a known commensal that colonizes skin, gastrointestinal tract and reproductive tract. The pathogenesis and prognosis of candidial infections are affected by the host immune status and they differ greatly according to disease presentations. Material Methods: 104 Candida isolates from various clinical specimens over a period of 6 months were identified by standard laboratory protocols and their antifungal susceptibility was done. Results: Candida species isolated were C.albicans – 54, C.tropicalis – 35, C. krusei – 09, C. glabrata & C. dubliensis – 03 each. All the species were highly sensitive to Nystatin and Itraconazole, moderately sensitive to Ketoconazole, Fluconazole and Amphotericin B. Discussion: The present study highlights the speciation of candida species by conventional techniques along with CHROM agar and increase in resistance to various antifungal agents amongst Candida albicans and NAC group.


Keywords


Candida, mucocutaneous, pathogenesis

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References


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