EVALUATION OF SINGLE DOSE VERSUS TRIPLE DOSE ANTIBIOTIC THERAPY IN PERIOPERATIVE PERIOD OF CLEAN VASCULAR SURGERY

Dr Ninad Kotkar, Dr Dwarkanath Kulkarni

Abstract


Infection is defined as invasion of the tissue by a pathogenic mirobes which establishes itself in host tissue, multiplies and results in tissue  damage due to release of toxic substances. Among surgical patients, surgical site infections (SSI) are the most common cause of nosocomial infection accounting for up to 38% of all such infections. The commonest and most dangerous complication in vascular surgery is prosthetic graft infection. Up to 2-5% of patients undergoing clean vascular surgery develop SSI. While handling infections, surgeons need to have knowledge of appropriate use of prophylactic and therapeutic antibiotics to mitigate high risk of morbidity and mortality. In this study, we have compared doses of antibiotics in perioperative period in clean vascular surgery, such as single versus triple dose.


Keywords


surgical site infections (SSI), nosocomial infections (NI), ANTIBIOTIC THERAPY

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References


Ananthanarayan R, Paniker C.K.J.: Infectin, Textbook of microbiology; 7th edition; 2006, chap.9 pg. 61.

Mangram AJ, Horan TC, Pearson ML. Guidelines for Prevention of Surgical Site Infections, 1999. Infection Control Hospital Epidemiology 1999; 20:250-72.

Vazquez Aragon P, Lizan-Garcia M, et al. Nosocomial infection and related risk factors in general surgery service : A prospective study. Journal of infection 2003; 46:17-22.

Bratzler WD, Houck MP. Antimicrobial prophylaxis for surgery : An advisory statement from the National Surgical Infection Prevention Project. Clinical Infectious Diseases 2004;38:1706-15.

C. Pratesi, D. Russo, et. al. Antibiotic prophylaxis in clean surgery : vascular surgery. Journal of chemotherapy December 2013; vol 13, no. sup4; pg 123-8.

Nicola P, Cecilia MJ, et. al. Surgical site infections in Italian Hospitals : a prospective multicentre study BMC Infectious Diseases 2008, 8:34.

Kirby JP, Mazuski JE. Prevention of surgical site infection. Surgical Clinics of North America, Apr 2009; Vol 89, No. 2: pg 365-84.

Lena MN. Perspectives in surgical infections : What does the future hold? Surgical infections, Indian edition, Vol 3, No. 1, July-Aug 2010; pg 1.


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