SEROPREVALENCE OF DENGUE VIRUS AMONG VOLUNTARY BLOOD DONORS IN CHENNAI –A CROSS SECTIONAL STUDY

Dr Chitra M, Dr Arumugam P, Dr Ravi Shankar J

Abstract


Background: Dengue is one of the common vectors borne viral infection with a serious threat of transfusion transmission particularly in dengue
endemic areas.
Aim: To find the seroprevalence of dengue virus among voluntary blood donors in Chennai.
Materials and Methods: 110 blood samples from VBD were collected in 1 year period from August 2014 to July 2015 and were subjected to
dengue NS1, IgM and IgG serological tests using InBios dengue ELISA kits.
Results: Among 110 VBD 91.8% of the donors were positive for anti- DENV IgG and none were positive for NS1 antigen or anti-DENV IgM.
Conclusion: There is a high seroprevalence of anti-DENV IgG (91.8%) in blood donors. All donor samples in this study were seronegative for
dengue NS1 and IgM


Keywords


Blood donors, dengue, Voluntary Blood Donors, nonstructural protein 1 antigen, immunoglobulin M, immunoglobulin G, screening ELISA test

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References


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