EFFECT OF COMMERCIALLY AVAILABLE GENERIC AND ETHICAL DRUGS AGAINST ISOLATED UROPATHOGENIC ESCHERICHIA: A STUDY
Abstract
The resistance pattern of uropathogens is increasing very rapidly because of the unsorted, insufcient and incoherent
usage of antibiotics. Urinary tract infection (UTI) is considered as a different type of infection which is caused by the
uropathogenic resistant bacteria. This infection is due to the main colonization of normal and opportunistic microora. The rate of UTI patients
is high due to poor hygiene, long time catheterization, uncontrolled sexual intercourse, pregnancy and spermicidal contraception. The present
study effect of Generic and Ethical drugs deal with on uropathogenic Escherichia species isolated from urine samples. In present study, total 50
samples were collected from ve pathology laboratories in Gondia City to isolate Uropathogenic Escherichia coli. However, only 44 Escherichia
spp. were isolated from collected urine samples. On the basis of morphological, cultural and biochemical characteristics, isolates were identied
as Escherichia. It is evident from the data that 100% Escherichia spp. isolated from urine samples were sensitive to both ethical and generic
Levooxacin whereas 88.6% Escherichia spp. isolated from urine samples were resistant to both ethical and generic Amoxicillin trihydrate after
24 – 48 hrs incubation. Using generic drug is more economic than ethical drug because it reduces burden of high cost of ethical drugs on patients
and lowers their expense on medicine.
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