NEUTROPHIL LYMPHOCYTES RATIO AS A PREDICTOR OF BACTEREMIA IN CHILDREN

Nurhasanah Lubis, Bugis Mardina Lubis, Syahril Pasaribu, Ayodhia Pitaloka Pasaribu

Abstract


Bacterial infections are an important problem in the world. Early and accurate diagnosis to detect infection is very important in order to reduce mortality. Many bacterial infections that cause leukocytes are circulating and are characterized by increased neutrophils and decreased lymphocytes, this is caused by the inflammatory process. The neutrophil lymphocyte ratio (NLR) is one of the infection markers currently being investigated because it is easy to do, simple with relatively low cost so that it can be used in daily practice. Research with a cross-sectional retrospective design on children performed blood culture at H. Adam Malik Hospital in 2017. Sampling was done in total population and a sample of 506 children who met the inclusion and exclusion criteria was obtained. Data analysis used the chai squared test   (p <0.05). This study looked at the 5 most bacteria, namely Klebsiella pneumonia, Acinetobacter baumanii, Staphylococcus aureus, Escherichia coli, Staphylococcus haemolyticus. The neutrophil lymphocyte ratio is better for determining bacteremia with sensitivity of 80.5%, specificity of 26.9%, positive predictive value of 33% and negative predictive value of 74% and cut off 1.3 but cannot be used as a guide because the relationship between blood culture and NLR is not significant with (p=0.1) and (OR=1.4)

Keywords


bacterial infection; blood culture; marker of infection; neutrophil lymphocyte ratio; predictor.

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References


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