CARDIO PROTECTIVE EFFECT OF WHEAT GRASS (TRITIUM AESTIVUM LINN) IN ALBINO RATS

Dr Annapoorna Sahoo, Dr Pravin Dhone

Abstract


Context: Cardiovascular disease (CVD) is the principal cause of death worldwide. Whole grain like
wheat (Tritium aestivum Linn.) may have cardioprotective effect.
Aims: This study was carried out to nd out the cardio-protective potential of Triticum aestivum Linn by observing its effect on
Isoproterenol induced myocardial infarction in rats.
Settings and Design: This was a longitudinal study done on thirty healthy albino rats
Methods and Material: Thirty albino rats were grouped into ve groups of six rats in each, and housed in separate cages groupwise.
All groups except control received Isoproterenol. In addition to Isoproterenol, two groups were given wheat grass at
different dosage and one group received Carvediliol. Cardiac parameters and histopathological study was done.
Statistical analysis used: ANOVA test and post hoc Dunnett test using SPSS version 16, unpaired t test
Results: Signicant reduction in cardiac parameters was seen.
Conclusions: Triticum aestivum prevented the Isoproterenol induced cardiotoxicity. Wheatgrass extract can be a good
alternative or primary therapy in treating cardiovascular diseases myocardial infarction in future.


Keywords


Tritium Aestivum Linn, Myocardial Infaraction

Full Text:

PDF

References


World Health Organisation. World Health Organisation Epidemiology and Burden of Disease Unit.Geneva, 2003.

Pierdomenico SD , Di Nicola M,Esposito AL,Di Mascio R,Ballone E,Lapenna D, et al. Prognostic value of different indices of blood pressure variability in hypertensive patients .Am J Hypertension .2009;22;842-7.

Chobanianav, Bakris GL, Black HR ,Cushman WC, Greeen LA,Izzo JL,Jr,et al. Seventh report of the joint national committee on prevention ,detection, evaluation, and treatment of high blood pressure.Hypertension,2003;42:1206-52.[Pubmed :14656957]

Pickering TG. Pathology of exercise hypertension.Herz .1987;12:119-24.[PubMed :2953661]

Kyrou I, Chrousos GP, Tsigos C. Stress, visceral obesity, and metabolic complications. Ann N Y Acad Sci.2006;1083:77-110.[PubMed :17148735]

Wofford MR, Hall JE. Pathophysiology and treatmengt of obesity hypertension. Curr Pharma Design .

Kulkarni SD, Tilak JC, Acharya R, Rajurkar NS, Devasagayam TPA, Reddy AVR. Evaluation of the antioxidant activity of wheatgrass (Triticum aestivum L.) as a function of growth under different conditions. Phytother Res 2006; 20: 218–227.

Padalia S, Drabu S, Raheja I, Gupta A, Dhamija M. Multiple potential of wheatgrass juice (green Blood): An overview. Chron Young Scientist 2010; 1: 23-28.

Sri jaya M, Gayathri S. Antioxidant activity of wheatgrass & impact of supplementing grass extract anaemics. Biomed 2009; 4: 262-268.

Othman AI, El-Missiry MA, Amer MA, Arafa M. Melatonin controls oxidative stress and modulates iron, ferritin, and transferrin levels in adriamycin treated rats. Life Sci. 2008;83:563–8.

Koti BC, Vishwanathswamy AH, Wagawade J, Thippeswamy AH. Cardioprotective effect of lipistat against doxorubicin induced myocardial toxicity in albino rats. Indian J Exp Biol. 2009;47:41–6.


Refbacks

  • There are currently no refbacks.