V. Jayakar Paul Benjamin, L. Sushanth Prabhath, S. Chithra, K. M. Keerthana


BACKGROUND AND OBJECTIVES: In the present study was investigated that the complications of infants of diabetic
between overt diabetic and gestational diabetes. A prospective study was conducted among infants of diabetic mothers
born at Meenakshi Medical College Hospital and Research Institute, Kanchipuram between October 2017 to October
2018. The morbidities in IDMs was studied and a comparison was made between infants born to women with
pregestational diabetes and gestational diabetes. The perinatal outcome was also studied.
METHODS: All consecutive live born babies born to diabetic mothers at Meenakshi Medical College Hospital and
Research institute between October 2017 to October 2018 were included in the study. IDMs were evaluated for
morbidities like macrosomia, birth asphyxia, congenital anomalies, birth inuries, respiratory distress, hypoglycemia,
hypocalcemia, hyperbilirubinemia and polycythemia. The neonatal complications in IDMs born to pregestational and
gestational diabetic mothers were compared and data was analyzed. The perinatal outcome of these IDMs was studied.
RESULTS: The complications seen in IDMs were LGA (20.6%), birth asphyxia (14.7%), Congenital anomalies (32.4%),
Respiratory distress (33.3%), RDS (6.1%), hypoglycemia (84.8%), hypocalcemia (3%), hyperbilirubinemia (21.2%) and
polycyhemia (6.1%). Hairy Pinna was observed in 52.9% of IDMs. Here were no significant statistical differences in the
incidence of complications among infants born to women with pregestational and gestational diabetes.
CONCLUSION: we conclude that the early intervention and management of pregnancies complicated by diabetes will
good neonatal care will result in decreased complications in IDMs and also will improve outcome in this high risk


Infant Of Diabetic Mothers; Diabetes In Pregnancy And Glycemic Control

Full Text:



Expert committee on the diagnosis and classification of Diabetes Mellitus: Report of the expert committee on the diagnosis and classification of Diabetes Mellitus. Diabetes care, 2003; 26 (1): S5 – S20.

Gabbe SG. Pregnancy in women with Diabetes Mellitus – The Beginning.

Clinics in perinatology, 1993; 20 (3) : 507 – 515.

Gabbe SG, Graves CR. Management of Diabetes Mellitus complicating pregnancy. Obstetrics and gynecology, 2003; 102 (4) : 857 – 868.

Diabetes. In: Cunningham GF, Leveno KJ, Bloom SL, Editors. Williams obstetrics, 22nd edition. Mc. Graw Hill. 1997 : 1169 – 1188.

Lucas MJ. Diabetes complicating pregnancy. Obstetrics and gynaecology clinics of North America, 2001; 28(3): 513 – 536.

Metzger BE, Buchanan TA, Coustan DR, et al. Summary and recommendations of the fifth international workshop conference on gestational diabetes mellitus. Diabetes care, 2007; 30(2): 251-260.

Setji TL, Brown AJ, Feinglos MN. Gestational Diabetes Mellitus. Clinical Diabetes, 2005; 23(1) : 17-24.

Quintero VH, Istwan NB, Rhea DJ, et al. The impact of glycemic control on neonatal outcome in singleton pregnancies complicated by gestational diabetes. Diabetes care, 2007; 30 : 467-470.

NNPD 2000. Report of the National Neonatology Forum, India: 2000.

Chmait R, Moore TR. Endocrine Disorders in pregnancy. In: Taeush, Ballard, Gleason, editors. Avery’s Diseases of the Newborn, 8th edition. 2005: 71-86.

Catalano PM, Alicia T. RD, Presley H. Phenotype of infants of mothers with gestational diabetes. Diabetes care, 2007; 30 (2) : S 156 – S 160.

Lee KG and Cloherty JP. Identifying the high risk newborn and evaluating gestational age, prematurity, postmaturity, large for gestational age and small for gestational age infants. In: Cloherty JP, Eichenwald EC, Stark AR, editors. Manual of Neonatal care, 5th edition; Philadelphia: Lippincott Williams and Wilkins. 2004: 42-56.

Martin CR, Cloherty JP. Neonatal Hyperbilirubinemia. In: Cloherty JP, Eichenwald EC, Stark AR, editors. Manual of neonatal care, 5th edition: Philadelphia: Lippincott Williams and Wilkins. 2004:185-221.

Ballard JL, Rosenn B, Khoury JC, et al. Diabetic fetal macrosomia: significance of disproportionate growth. The Journal of Pediatrics, 1993; 122 (1): 115-119.

Sudarshan K, Jain S, Jain RK, et al. Study of morbidity and mortality pattern in infants born to diabetic mothers. Journal of Obstetrics and Gynaecology of India, 1987; 37: 481 - 484

Deorari AK, Kabra SK, Paul VK, et al. Perinatal outcome of infants born to diabetic mothers. Indian Pediatrics, 1991; 28: 1271-1275.

Mangala R, Mhaskar R, Mhaskar A, et al. Perinatal outcome in pregnancies complicated by diabetes. International journal of diabetes in developing countries, 1991; 11: 22 – 24.

Watson D, Rowan J, Neale L, et al. Admissions to neonatal intensive care unit following pregnancies complicated by gestational and type 2 diabetes mellitus. The Australian and New Zealand journal of Obstetrics and Gynaecology, 2003; 143 (6): 429 – 432.

Gabbe SG, Lowensohn RI, Wu PY, et al. Current patterns of neonatal morbidity and mortality in infants of diabetic mothers. Diabetes care, 1978; 1(6): 335 – 339.


  • There are currently no refbacks.