INTRATHECALLY BUPRENORPHINE WITH 0.5% HEAVY BUPIVACAINE FOR POSTOPERATIVE ANALGESIA IN CESAREAN SECTION: A RANDOMISED CONTROL TRIAL.

Dr. Mohammed Irfan, Dr. Mohammed Mishal, Dr. S. P. Chittora

Abstract


This study was aimed to evaluate the effect of addition of intrathecal Buprenorphine to Bupivacaine heavy 0.5% on post operative analgesia in caesarian sections and the side effects associated with use of Buprenorphine. Method: Sixty patients posted for elective caesarian sections were randomly divided in two groups of 30 patients each. Patient received either 1.7 ml 0.5% Bupivacaine with + 0.3ml NS (Group A) or 1.7 ml 0.5% Bupivacaine with 90 mcg (0.3ml) buprenorphine (Group B) intrathecally.

Results: Onset of analgesia was 3.2±0.2 min in group A while in group B 1.9±.1.42 min. Duration of postoperative analgesia was significantly prolonged in Group B (661.63±96.33min) than Group A (180.60±20.86min). Addition of buprenorphine 90μg to intrathecal bupivacaine prolonged the duration of postoperative analgesia after LSCS without effect of on neonatal Apgar score and with minimal maternal side effect.


Keywords


Bupivacaine , Buprenorphine, Visual Analogue Scale.

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References


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