Dr. Deba Gopal Pathak, Dr. Peter Engti


BACKGROUND: Spinal anaesthesia is the most commonly used technique for lower abdominal, lower limb surgeries. In clinical practice both Fentanyl and buprenorphine have been used as adjuvants with bupivacaine for spinal anesthesia. So, this present study has been conducted to assess the better drug between these two adjuvants with regard to post-operative analgesia and haemodynamic stability.

OBJECTIVE: To study the effects of 0.5% hyperbaric bupivacaine with buprenorphine and 0.5% hyperbaric bupivacaine with fentanyl in spinal anaesthesia for lower abdominal and lower limb surgeries.

SETTINGS & DESIGN: This comparative study included 50 patients in two groups, of ASA class I & II undergoing lower abdominal and lower limb surgeries under spinal anesthesia after approval from hospital ethics committee with written informed consent of patients.

MATERIALS AND METHODS: Patients were categorized into two groups (n=50) A & B. Group A received 75μg of buprenorphine and Group B received 25μg of fentanyl as adjuvants to 15mg of 0.5% hyperbaric bupivacaine (3.0ml). Onset of sensory block and motor block, two segment regression, time of sensory and motor block, duration of sensory & motor block, duration of analgesia, haemodynamic changes and side effects were recorded.

RESULTS: There was no significant difference in onset of sensory block in two groups (P>0.05), but onset of motor block was significantly earlier in buprenorphine group. Two segment regression time, duration of sensory & motor block, duration of analgesia were significantly longer for group A as compared to group B (P< 0.05).

CONCLUSION: The duration of sensory block, motor block and duration of post-operative analgesia was better in buprenorphine group in comparison to fentanyl group. Both the drugs prolong the duration of analgesia on giving intrathecally along with bupivacaine heavy. These drugs can be used to prolong duration of analgesia in lower abdominal and lower limb surgeries without having any significant side effect.


Spinal anaesthesia, Intrathecal hyperbaric bupivacaine, Buprenorphine, Fentanyl.

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