ASSOCIATION OF KIDNEY FUNCTIONS WITH 30 DAY POST STROKE MORTALITY

Ismail M. Haji, Ashrith Ma, Shaheen B, Mukhtarahamed B

Abstract


Background: Renal impairment most witnessed in hospitalized stroke patients, affecting the outcome of patients, as well as causing difficulties in their management. Association of renal dysfunction in post stroke mortality is important in outcome studies and risk standardization in hospital readmission rates. This study was designed and conducted with aim to evaluate the prevalence of renal dysfunction in patients after stroke and the 30 day mortality impact in post stroke patients. Materials and methods: This was a retrospective study where data was collected from medical records of 40 patients admitted to ICU with a diagnosis of stroke dated from January 2018 to December 2019. The data were analyzed in the terms of demographic details, risk factors for stroke, pulse rate, mean arterial pressure, pulse pressure, plasma glucose and renal function tests at the admission. Estimated glomerular filtration rate was calculated by Chronic Kidney Disease Epidemiology Collaboration. All patients records were traced upto 30 days post stroke. Results: The statistical analysis were done with SPSS version 24.0. Time of survival was evaluated with multivariate Cox proportional hazard analysis. Results were expressed as hazard ratio (HR) and its 95% confidence interval (95% CI). A total of 23 patients expired during 30 day period of time following stroke. The independent predictors of death remained: age, eGFR <60 ml/min/1.73 m2, proteinuria and glucose at a concentration >100 mg/dl. Conclusion: In patients with stroke, the impaired kidney function expressed by low eGFR with or without the presence of proteinuria is a powerful and an independent prognostic factor for short-term survival.


Keywords


Stroke, Glomerular filtration rate, Proteinuria, Renal dysfunction

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References


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