SERUM URIC ACID AS A MARKER OF CAD IN TYPE II DM

Dr. Keshav Singh, Dr. Praveen Tagore, Dr. Jal Singh Narwaria, Dr. Rakesh Patel

Abstract


BACKGROUND: The Morbidity and mortality due to non-communicable diseases specially attributed to diabetes
mellitus (DM) and coronary Artery disease (CAD) is rising rapidly in India, causing nearly 5.8 million deaths per year
annually. Considering the strong association between the levels of serum uric acid (SUA) and the occurrence of coronary
atherosclerosis in subjects with type 2 diabetes mellitus, the current study has been undertaken to assess the factors
influencing the serum uric acid levels in patients with type 2diabetes mellitus.
AIMS AND OBJECTIVES: 1.To study the level of SUA in patients with type 2 DM, 2.To establish the association of
elevated serum uric acid concentration as a risk factor for CAD in type–2 diabetes patients.
RESULTS: Mean serum uric acid value is significantly higher in type II diabetes patients (5.76±1.15) than controls
(3.39±0.56). Mean serum uric acid value is significantly higher in Diabetic patients with CAD (6.115±0.87) than non CAD
patients (5.43±0.59).
CONCLUSION: Level of serum uric acid is related to duration of diabetes mellitus. It is an independent predictor of CAD
in DM patients thus can be used as a marker of CAD in type II DM patients.


Keywords


Serum Uric Acid, Diabetes Mellitus, Coronary Artery Disease

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