Naik. N. V


It is observed that 60-90% of the patients have some underlying immune suppressive condition such as chronic steroid use,
solid organ transplantation, malignancy or human immunodeficiency virus (HIV) infection, the growing problem of mucosal
and systemic candidiasis reflects the enormous increase in the number of such patients at risk and the increased
opportunity that exists for Candida species to invade tissues normally resistant to invasion .These patients are in a state in
which the immune system's ability to fight infectious disease is compromised or entirely absent and become vulnerable to
opportunistic infections, in addition to normal infections that could affect everyone. Widespread usage of antifungal has
rapidly led to the increasing cases of drug resistance which emerges as a threat to the antifungal therapy and therefore there
is an urgent need for novel therapies against this pathogen. The use of plants as sources of pharmaceutical drugs that are
used in traditional medicine need to be tested for its antimicrobial action towards these isolates


immune compromised, antimicrobial, opportunistic pathogen,

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