CLINICAL SPECTRUM AND DETECTION OF MYCOPLASMA PNEUMONIAE IN INFANTS WITH WHEEZE IN COMMUNITY ACQUIRED PNEUMONIA

Dr Surinder Kumar, Dr Urvashi Suman

Abstract


Mycoplasma pneumoniae (M. pneumoniae) is the leading atypical bacterial pathogen responsible for lower respiratory tract
infection including infants, which is often associated with wheeze. We studied 55 infants up to 24 months of age having
community acquired pneumonia presenting with acute wheeze. Cough and fever were most common symptoms while
consolidation and infiltrates were most common radiographic abnormality present. M. pneumoniae was determined by
detecting immunoglobulin (Ig) M antibody in blood by employing enzyme linked immunosorbent assay (ELISA) as well as
detecting P1 adhesin gene by polymerase chain reaction (PCR) in nasopharyngeal aspirate. M. pneumoniae was found to be
positive in 16.4% cases employing both the tests. Our study confirms the role of M. pneumoniae in infants presenting with
wheeze which often misdiagnosed as viral pneumonia due to overlapping symptoms.


Keywords


Mycoplasma pneumoniae, IgM, PCR, Atypical Pneumonia

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