DESCRIPTIVE ANALYSIS OF LATERALITY IN LUNG CANCER AND SMOKING IN QUITOECUADOR

Ayala Brito Rosa Guadalupe, Pazmiño Navarrete María Teresa, Cañarte Santana María Gabriela, Rivera Salas Javier Alexander, Vizcaíno Cevallos Betsabé Patricia, Zabala Aguilar Mayra Alexandra, Montaluisa Pilatasig Johana Natali, Arévalo Jaramillo María Daniela

Abstract


Introduction: In Ecuador, lung cancer ranks eighth in men and ninth in women according to the National Tumor Registry,
however, it has little research in our country.
The objective of this research is to describe a relationship between the location of lung cancer and laterality.
Methods: 37 histopathological samples were analyzed during the years 2012-2016 using descriptive analysis of
frequency as well as crossing of variables.
Results: Of the 37 patients, 7.3% correspond to non-smokers, 3.1% to smokers in the past and 4.2% current smokers, the
rest corresponds to ignorance of this practice.
Regarding location in non-smoking patients, it is located in the upper lobe in 57%, while smokers in the past have a
greater predisposition to be located in the lower lobe in 17% with an OR = 2.25 95% CI (0 , 61-8.18); p = 0.15, while
current smokers are more likely to develop a tumor in the left lung over the right and there is no laterality relationship
between smokers in the past and non-smokers.
Conclusion: The distribution of lung cancer in our research is similar to that demonstrated in international studies in
which right lung cancer occurs more frequently than the left one, as well as the upper lobe above the lower one, having to
recommend that we should start prospective studies and evaluate survival according to laterality.


Keywords


Lung, cancer, smoke, Ecuador, Quito

Full Text:

PDF

References


Villacrés L. RETROSPECTIVE VISION OF LUNG CANCER IN ECUADOR. PARIPEX - INDIAN J Res. 2019;8(1):411–3.

SOLCA. EPIDEMIOLOGÍA DEL CÁNCER EN QUITO 2006-2010 [Internet]. 15th ed. Cueva P, editor. Quito; 2014. Available from: http://www.estadisticas.med.ec/Publicaciones/PUBLICACION-QU-2006-2010.pdf

McWilliam A, Vasquez Osorio E, Faivre-Finn C, van Herk M. Influence of tumour laterality on patient survival in non-small cell lung cancer after radiotherapy. Radiother Oncol. 2019;

Roychoudhuri R, Putcha V, Møller H. Cancer and laterality: A study of the five major paired organs (UK). Cancer Causes Control. 2006;

Alghamdi HI, Alshehri AF, Farhat GN. An overview of mortality & predictors of small-cell and non-small cell lung cancer among Saudi patients. J Epidemiol Glob Health [Internet]. Ministry of Health, Saudi Arabia; 2018 Mar;7(6800):S1–6. Available from: https://doi.org/10.1016/j.jegh.2017.09.004

Jørgensen N, Meline EL, Jeppesen SS, Hansen O, Nielsen M, Schytte T. The effect of tumor laterality on survival for non-small cell lung cancer patients treated with radiotherapy. Acta Oncol (Madr) [Internet]. Taylor & Francis; 2019 Oct 3;58(10):1393–8. Available from: https://doi.org/10.1080/0284186X.2019.1629011

Jia B, Zheng Q, Qi X, Zhao J, Wu M, An T, et al. Survival comparison of right and left side non‐small cell lung cancer in stage I–IIIA patients: A Surveillance Epidemiology and End Results (SEER) analysis. Thorac Cancer [Internet]. 2019 Mar 9;10(3):459–71. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/1759-7714.12959

Kudo Y, Saji H, Shimada Y, Nomura M, Usuda J, Kajiwara N, et al. Do tumours located in the left lower lobe have worse outcomes in lymph node-positive non-small cell lung cancer than tumours in other lobes? Eur J Cardio-Thoracic Surg [Internet]. 2012 Sep 1;42(3):414–9. Available from: https://academic.oup.com/ejcts/article-lookup/doi/10.1093/ejcts/ezs065


Refbacks

  • There are currently no refbacks.