ELECTROLYTE ABNORMALITIES IN CRITICALLY ILL CHILDREN
Abstract
OBJECTIVES: To study the frequency of electrolyte and blood glucose imbalance at admission in children admitted to a Pediatric Intensive Care
Unit (PICU).
METHOD: Prospective study comprising of critically ill children admitted in Pediatric ICU of a tertiary care centre of North Karnataka from
November 2015 to April 2017.
RESULTS: One hundred and fty three patients aged 1mo to 15y, were admitted to the PICU during the study period. The mean age was 4.8 y. The
male: female ratio was 1.2:1.128 patients (83.7%) had electrolyte abnormality. Hypochloremia was the most common electrolyte abnormality,
followed by hyponatremia, hyperglycemia. Most common system involved was CNS, followed by Respiratory illness. Out of the 153 patients,
96.1% were discharged, 3.3% were discharged against medical advice, 0.7% died.
CONCLUSION: Serum electrolyte and blood glucose abnormalities are very common in critically ill patients and can lead to fatal consequences.
In view of these facts, a routine estimation of serum electrolytes and blood glucose should be considered in all patients getting admitted to PICU.
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Lee JW. Fluid and electrolyte disturbances in critically ill patients. Electrolyte Blood press 2010; 8:72-81.
Subba Rao SD, Thomas B .Electrolyte abnormalities in children admitted to pediatric intensive care unit. Indian Paediatrics 2000; 37:1348-53.
Linda F. Fried MD, Paul M. Palevsky MD: Hyponatremia and hypernatremia. Medical Clinics of North America - Volume 81, Issue 3 (May 1997) - Copyright © 1997 W. B. Saunders Company.
Larry A. Greenbaum. Electrolyte and acid-base disorders. In:Kleigman, Behrman, Jenson, Stanton editors. Nelson textbook of pediatrics, 18th ed.Elsevier;1; 52; 375
Srivastava RN Arvind B. Fluid, Electrolyte and Acid – base disorders.In: Priyanka Khandelwal, Arvind Bagga. Pediatric nephrology. 6thed India.2016;100-115.
Paul VK, Bagga A. Fluid and Electrolytes. In: Kamaran Afzal. Ghai Essential of Pediatrics.8th ed. India, Delhi.2013; 70-87.
Morrison G. Serum Chloride. In: Walker HK, Hall WD, Hurst JW, editors. Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition. Boston: Butterworths; 1990. Chapter 197.
Bhutia, Tsultem D. Abnormaltites in glucose homeostasis in critically ill children. 2013;14:e16-e25
Adelman RD, Soihaug MJ. “Pathophysiology of body fluids and fluid
therapy”. Nelson Textbook of Pediatrics, 19th Edition, Vol. 1 Eds Behrman RE, Kilegman RM, Jenson HB. Philadelphia. W.B. Saunders, 2000; 189-196
Tani, Makiko & Morimatsu, Hiroshi & Takatsu, Fumiaki & Morita, Kiyoshi. (2012). The Incidence and Prognostic Value of Hypochloremia in Critically Ill Patients. TheScientificWorldJournal. 2012. 474185. 10.1100/2012/474185.
Singhi S, Prasad SVSS, Chugh KS. “Hyponatremia in sick children: a marker of serious illness”. Indian Pediatrics. 1994; 31:19 - 25.
Rey, Corsino & Los-Arcos, Marta & Hernández, Arturo & Sánchez, Amelia & Diaz, Juan & López-Herce, Jesús. (2011). Hypotonic versus isotonic maintenance fluids in critically ill children: A multicenter prospective randomized study. Acta paediatrica (Oslo, Norway: 1992). 100. 1138-43.
Jeremy N Friedman; Canadian Paediatric Society Acute Care Committee Paediatr Child Health 2013;18(2):102-104
Srinivasan V, Spinella PC, Drott HR, Roth CL, Helfaer MA, Nadkarni V. Association of timing, duration, and intensity of hyperglycemia with intensive care unit mortality in critically ill children. Pediatr Crit Care Med. 2004; 5(4):329–36.
Jain H, Arya S, Mandloi R.The prevalence of hyperglycemia in critically ill children admitted in PICU. Int J Pediatr Res.2016; 3(6):467-471.
Sivanandan, Sindhu & Sinha, Aditi & Jain, Vandana & Lodha, Rakesh. (2010). Management of Diabetic Ketoacidosis. Indian journal of pediatrics. 78. 576-84. 10.1007/s12098-010-0294-8.
Zofkova L. Hypercalcaemia pathophysiological aspects. Physiol Res. 2015; 65:1–10.
Goltzman D. Hypercalcemia. In: De Groot LJ, Chrousos G, Dungan K, et al., editors. Endotext . South Dartmouth (MA): MDText.com, Inc.; 2000-226.
S. Singhi and A. Marudkar, hypokalemia in pediatric intensive care unit
November 17, 1994; Accepted: April 17, 1995.
Sacha PB, Maneesh B, Alexander Z. The use of modified lactated ringer solution prevents hyperchloremia in critically ill neurological patients. American jornal of respiratory and critical care medicine 2013; 187:A 1598.
Vriesendorp TM, van Santen S, DeVries JH, et al: Predisposing factors for hypoglycemia in the intensive care unit. Critical care medicine.2006; 34;96-101
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