COMBATING KOCURIA: A GAME OF SHADOWS
Abstract
INTRODUCTION: Kocuria species is now an upcoming pathogen. They are gram-positive cocci and are catalase positive but coagulase
negative, hence causing confusion with coagulase negative staphylococci. There are no CLSI guidelines for antibiotic sensitivity testing yet
established for this pathogen. Here we present some cases in the pediatric age group caused by Kocuria spp.
MATERIALS AND METHODS: Kocuria spp. were isolated from 28 different clinical samples. The morphological and biochemical features
suggestive of Kocuria were confirmed by Vitek-2 system. Susceptibility testing was performed according to the CLSI guidelines for
Staphylococcus.
RESULTS: We found four Kocuria spp. causing infections – K. kristinae, K. rosea, K. varians and K. rhizophila. Out of 28 isolates, 13 were
multidrug resistant.
CONCLUSION: Insufficient literature is available to establish antibiotic susceptibility profile of this bacteria. Available data show it to be broadly
susceptible to most of the antibiotics. However, the present study showed a different picture.
Keywords
Full Text:
PDFReferences
Becker K, Rutsch F, Uekotter A, Kipp F, Konig J, Marquardt T et al. Kocuria rhizophila
adds to the emerging spectrum of micrococcal species involved in human infections. J Clin Microbiol 2008;46:3537–3539.
Lee JY, Kim SH, Jeong HS, Oh SH, Kim HR, Kim YH et al. Two cases of peritonitis caused by Kocuria marina in patients undergoing continuous ambulatory peritoneal dialysis. J Clin Microbiol 2009;47:3376–3378.
K v, Ramana & Palange, Padmavali & Vaish, Ritu & Bashir Bhatti, Adnan & Kale, Vinod & Reddy Kandi, Maheshwar & Rao Bhoomagiri, Mohan. (2016). Emerging Bacterial Infection: Identification and Clinical Significance of Kocuria Species. Cureus. 8. 10.7759/cureus.731.
Boudewijns M, Vandeven J, Verhaegen J, Ben-Ami R, Carmeli Y. Vitek 2 automated identification system and Kocuria kristinae. J Clin Microbiol 2005;43:5832
The expanding spectrum of human infections caused by Kocuria species: a case report and literature review. Shashikala Purty, Rajagopalan Saranathan, K Prashanth, K Narayanan, Johny Asir, Chandrakesan Sheela Devi et al.
Emerg Microbes Infect. 2013 Dec; 2(12): e91. Published online 2013 Dec 18. doi: 10.1038/emi.2013.93
Basaglia G, Carretto E, Barbarini D, Moras L, Scalone S, Marone P et al. Catheter-related bacteremia due to Kocuria kristinae in a patient with ovarian cancer. J Clin Microbiol 2002;40:311–313.
Ma ESK, Wong CL, Lai KT, Chan EC, Yam WC, Chan AC. Kocuria kristinae infection associated with acute cholecystitis. BMC Infect Dis 2005;5:60.
Lai CC,Wang JY,Lin SH, Tan CK, Wang CY, Liao CH et al. Catheter-related bacteraemia and infective endocarditis caused by Kocuria species. Clin Microbiol Infect 2011;17:190–192.
Martinaud C, Gisserot O, Gaillard T, Brisou P, de Jaureguiberry JP. Bacteremia caused by Kocuria kristinae in a patient with acute leukaemia. Med Mal Infect 2008;38:334–335.
Tsai CY, Su SH, Cheng YH, Chou YL, Tsai TH, Lieu AS. Kocuria varians infection associated with brain abscess: a case report. BMC Infect Dis 2010;10:102.
Becker K, Rutsch F, Ueko¨tter A et al. Kocuria rhizophila adds to the emerging spectrum of micrococcal species involved in human infections. J Clin Microbiol 2008;46:3537–3539.
Kaya KE, Kurtoglu Y, Cesur S et al. [Peritonitis due to Kocuria rosea in a continuous ambulatory peritoneal dialysis case.] Mikrobiyol Bul 2009;43:335- 337.
J Microbiol Immunol Infect. 2015 Feb;48(1):80-4. doi: 10.1016/j.jmii.2013.07.001. Epub 2013 Aug 19. Kocuria kristinae: a true pathogen in pediatric patients. Chen HM, Chi H, Chiu NC, Huang FY.
First report of Kocuria marina spontaneous peritonitis in a child. Gabriel Brändle, Arnaud G L’Huillier, Noémie Wagner, Alain Gervaix, Barbara E Wildhaber and Laurence Lacroix, Brändle et al. BMC Infectious Diseases (2014) 14:719DOI 10.1186/s12879-014-0719-5.
Endocarditis by Kocuria rosea in an immunocompetent child. Jorge SalomãoMoreiraa, Adriana Gut Lopes Riccetto, Marcos Tadeu Nolasco da Silva, Maria Marluce dos SantosVilela. The Brazilian Journal of Infectious Diseases Volume 19, Issue 1, January–February 2015, Pages 82-84 https://doi.org/10.1016/j.bjid.2014.09.007.
Report of two pediatric cases of central line infections caused by species of the genus Kocuria. Sejal Makvana Bhavsar, Camille L. Hamula and Tanis C. Dingle. .JMM Case Reports (2016. 6) DOI 10.1099/jmmcr.0.005.
Lee JY, Kim SH, Jeong HS, et al: Two cases of peritonitis caused by Kocuria marina in patients undergoing continuous ambulatory peritoneal dialysis. J Clin Microbiol. 2009, 47:3376–3378. 10.1128/JCM.00847-09.
Meletis G, Gogou V, Palamouti M, et al.: Catheter-related relapsing peritonitis due to Kocuria varians in a patient undergoing continuous ambulatory peritoneal dialysis. Nefrología (Madr. 2012, 32:541–2. 10.3265/Nefrologia.pre2012.Apr.11471.
Moissenet D, Becker K, Mérens A, et al.: Persistent bloodstream infection with Kocuria rhizophila related to a damaged central catheter. J Clin Microbiol. 2012, 50:1495–8. 10.1128/JCM.06038-11.
Refbacks
- There are currently no refbacks.