Dr. Aditya Sood, Dr. (Prof.) Deepak Joshi, Dr Sushmita Kushwaha, Dr. (prof.) R. K. Arya, Dr. (prof.) Sunil Ranga


Introduction: Rotator cuff tendinopathy is one of the most common cause of chronic shoulder pain and disability.

Aim: To compare the efficacy of PRP injection versus corticosteroid injection in the treatment of Supraspinatus tendinopathy.

Design: Prospective randomized study.

Methods: 100 patients with Supraspinatus tendinopathy were randomized into two groups of 50 each. Group A received subacromial corticosteroid injection while group B received Platelet rich plasma injection. Treatment outcomes were assessed at 2weeks, 6weeks and 3months following injection using CMS, VAS and SPADI scores.

Results: Reduction in pain and improvement in functional scores were evident in both the groups at each follow up, as assessed by VAS, Constant and SPADI scores. Mean VAS scores were significantly better in Corticosteroid group at 2 weeks(p=0.003) and  in PRP group at 3 months(p=0.037) following injection. . Constant score (CMS) showed better percentage improvement  with  Corticosteroid injection than the PRP injection at 2 weeks (p<0.0001) and 6 weeks (0.004) but not at 3 months (p=0.093). Mean SPADI scores were non-significant in both the groups at each follow ups.

Conclusion: Corticosteroid injection is better in short term relief but in long term  term both PRP and steroid had similar effects.


corticosteroid; platelet rich plasma; rotator cuff tendinopathy.

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Chakravarty K, Webley M (1993) Shoulder joint movement and its relationship to disability in the elderly. J Rheumatol 20(8):1359–1361.

Kim HM, Dahiya N, Teefey SA et al (2010) Location and initiation of degenerative rotator cuff tears. J Bone Joint Surg (Am) 92(5):1088–1096 .

Luime J, Koes B, Hendriksen I, Burdorf A, Verhagen A, Miedema H, Verhaar J (2004) Prevalence and incidence of shoulder pain in the general population; a systematic review. Scand J Rheum 33(2):73–81.

Neer CS (1972) Anterior acromioplasty for the chronic impingement syndrome in the shoulder: a preliminary report. J Bone Joint Surg 54(1):41–50.

Scarpone M, Rabago D, Snell E et al (2013) Effectiveness of platelet-rich plasma injection for rotator cuff tendinopathy: a prospective open-label study. Glob Adv Health Med 2(2):26–31.

Mantone JK, Burkhead WZ Jr, Noonan J Jr. Nonoperative treatment of rotator cuff tears. Orthop Clin North Am. 2000;31:295-311.

Browning DG, Desai MM. Rotator cuff injuries and treatment. Prim Care. 2004;31:807- 829.

Ho JO, Sawadkar P, Mudera V.A review on the use of cell therapy in the treatment of tendon disease and injuries. J Tissue Eng 2014;18(5):204–213.

Anitua E, Andı´a I, Sanchez M, Nurden TA, Nurden P, Azfora J et al. Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture. J Orthop Res 2005;23:281–286.

S Saunders,S Longworth. Injection Techniques in Musculoskeletal Medicine:A Practical Manual for clinicians in Primary & Secondary Care ; Churchill Livingstone ,2011

Wehren LV, Blanke F ,Todorov A ,Patricia H , Sailer J , Majewski M . The effect of sub acromial injections of autologous conditioned plasma versus cortisone for the treatment of symptomatic partial tears ,European Society of Sports Traumatology, Knee Surgery, Arthroscopy(ESSKA) 2015 ;24(12):3787-3792.

Lin MT, Chiang CF, Wu CH, Huang YT, Wang TG et al. Comparative Effectiveness of

Injection Therapies in Rotator Cuff Tendinopathy: A Systematic Review, Pairwise and

Network Meta-analysis of Randomized Controlled Trials. Archives of Physical Medicine

& Rehabilitation 2019;100(2):336-349.

Damjanov N, Barac B, Colic J ,Tulic G, Zekovic V et al.The efficacy and safety of

autologous conditioned serum (ACS) injections compared with betamethasone and placebo

injections in the treatment of chronic shoulder joint pain due to supraspinatus tendinopathy:

A prospective, randomized, double-blind, controlled study.Med Ultrason 2018;20(3);335-341.

Rha DW, Park GY, Kim YK, Kim MT, Lee SC. Comparison of the therapeutic effects of ultrasound-guided platelet-rich plasma injection and dry needling in rotator cuff disease: a randomized controlled trial. Clin Rehabil. 2013;27:113-122.

Scarpone M, Rabago D, Snell E, Pritchard P, Ruppert K, Wilson JJ et al.Effectiveness of platelet-rich plasma injection for rotator cuff tendinopathy: a prospective open-label study. Glob Adv Health Med 2013;2(2):26–31.

Maman E, Yahuda C, Pritsch T, Morag G, Brosh T et al.Detrimental Effect of Repeated

& Single Subacromial Corticosteroid Injections on the Intact and Injured Rotator Cuff: A Biomechanical & Imaging study in Rats. American Journal Of Sports Medicine 2015; 44(1):177-182.


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