A STUDY OF SERUM CALCIUM AND PHOSPHORUS IN PSORIASIS

Praful Ramteke, Rahul R. Gadpal, B B Murhar, Reena V Wagh

Abstract


INTRODUCTION
Globally, psoriasis affects approximately 125 million people1 It is a .
serious global problem and the prevalence of psoriasis in different
countries ranges between 0.09% and 11.4%2,3 Psoriasis is a .
hyperproliferative diseases because there is an increase of frequency of
epidermis basal cells contributing in mitosis is seen in this disease.
Several studies have observed the close association between psoriasis
and serum calcium level.Intracellular calcium plays an important role
in the regulation of proliferation and differentiation of
keratinocytes4 Association of pustular psoriasis of von Zumbush, a .
rather severe form of psoriasis with mild hypocalcemia has been
observed5 Even hypoparathyroidism may aggravate psoriasis in .
patients with surgical hypoparathyroidism and primary
hypoparathyroidism6.There are very few studies done in India to assess
the serum calcium, phosphoruslevel in psoriasis patients, hence the
present study


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References


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