Dr. Chethan Sagar S, Dr Radha S Angadi, Dr Ramesh Babu K


Back ground: The Bethesda system for reporting thyroid cytopathology (BSRTC) stratifies thyroid fine needle aspirations (FNAs) into 6 main
diagnostic categories and conveys uniform language among pathologists and clinicians. It has standardized the diagnostic approach to
cytomorphological criteria and reporting.
Aim: To evaluate the results of FNAC in diagnosis of thyroid lesion using Bethesda system of reporting
Materials and methods: We retrospectively revived one year thyroid FNAs and classified according to BSRTC.
Results: Total 150 thyroid FNAs were reviewed and categorized into diagnostic categories of Bethesda system. Among those 72% belonged to
benign category (Bethesda 2), followed by Non diagnostic (Bethesda 1), 13%, Malignant (Bethesda 6) 6%, Follicular
neoplasm (Bethesda 4) 5% and both Suspicious for malignancy (Bethesda 5) and Atypia of undetermined significance (Bethesda 3) 2% each.
Conclusion: Interpretation of thyroid FNA varies from one laboratory to another resulting
in diagnostic ambiguity in few cases. Application of BSRTC may bring in objective guidelines for reporting thyroid cytopathology.


Bethesda, Cytopathology of thyroid, Fnac thyroid.

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Wang HH. Reporting thyroid fine-needle aspiration: literature review and a proposal.

Diagnostic Cytopathology 2006;34(1):67-76.

Cibas ES, Ali SZ: Bethesda system for reporting thyroid cytopathology . Thyroid 2009,

(11): 1159-65.

Cibas ES. Fine-needle aspiration in the work-up of thyroid nodules. Otolaryngol Clin

North Am 2010;43(2):257-271.

Lewis CM, Chang KP, Pitman M, et al. Thyroid fine-needle aspiration biopsy: variability

in reporting. Thyroid 2009;19(7):717-723.

Mondal SK, Sinha S, Basak B, et al. The Bethesda system for reporting thyroid fine

needle aspirates: a cytologic study with histologic follow-up. J Cytol 2013;30(2):94-99.

Mehra P, Anand AK. Thyroid cytopathology reporting by the Bethesda system: a twoyear

prospective study in an academic institution. Pathology Research International

Article ID,240505, 2015 :10-11

Bongiovanni M, Spitale A, Faquin WC, Mazzucchelli L, Baloch ZW . TheBethesda

System for Reporting Thyroid Cytopathology: a meta-analysis . Acta Cytol .

;56:333-9 . Epub July 25, 2012; doi: 10 .1159/000339959

Tahir SM, Molah R. The Bethesda system for reporting thyroid cytopathology: A five

year retrospective review of one center experience. Int JHealth Sci 2012;6(2):131-43

Her-Juing Wu H, Rose C, Elsheikh TM .The Bethesda system for reporting thyroid

cytopathology: An experience of 1,382 cases in a community practice setting with the

implication for risk of neoplasm and risk of malignancy. Diagn Cytopathol 2011;

(6):4p. doi: 10.1002/dc.21754.

Lee K, Jung C K , Lee K Y , Bae JS , Lim DJ, Jung S L. Application of Bethesda System

for Reporting Thyroid Aspiration Cytology. Korean J Pathol 2010; 44(5): 521-7.

Shilpa N, Ramesh B, Implementation of Bethesda System for Reporting Thyroid

Cytopathology. International journal of scientific research.2006; 5(7): 527-28


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