Dr Monali Rewatkar, Dr Arun Tadas, Dr Kshama Kedar, Sanjay Agrawal, Supriya Bhoyar, Aditya Jain


Background Preterm birth (<37 completed weeks gestation) and very low birth weight (VLBW; <1500g) are associated with elevated maternal serum uric acid level. Uric acid is a marker of oxidative stress,tissue injury & endothelial dysfunction. It increases risk of preterm delieveries & can cause poor fetal outcome like foetal distress,IUGR babies etc

Materials & Methods - 100  women admitted in OBGY ward in last trimester of pregnancy were selected and follow up study was taken till delivery. Serum Uric acid level was estimated in Biochemistry clinical Laboratory on Autoanalyser in all subjects at term & values was estimated and compared with Mode of their delivery. Level of Serum uric acid was compared with IUGR & fetal distress & their association was correlated.

Result –                                                                            

Our study shows positive correlation between increase level of serum uric acid & Preterm deliveries  which shows association of hyperuricemia with Preterm labour. Current study also shows that there is positive and statistically significant relationship between hyperuricaemia in Pregnant women with  fetal  complications like IUGR, foetal distress, premature deliveries  etc .

Conclusion –  Increase serum uric acid level increases risk of preterm labours & fetal complications. So early screening for Serum uric acid level must be advised in pregnancy to prevent further risk like foetal distress & IUGR babies. 



Preterm delieveries,Foetal distress, Serum Uric acid

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