PRESCRIBING PATTERN OF ANTIMICROBIAL AGENTS IN MEDICAL INTENSIVE CARE UNIT OF A SUBURBAN TERTIARY CARE TEACHING HOSPITAL IN NORTH INDIA

Dr. Dinesh Kumar Yadav, Dr. Vinod Kapoor, Dr. Poonam Salwan, Dr. Kapil Hazarika

Abstract


Background : This prospective observational study was conducted to evaluate prescribing pattern of antimicrobial agents (AMAs) in the Medical intensive care unit (MICU) of a suburban tertiary care teaching hospital in Haryana. The ultimate aim is to achieve rational prescription of AMAs so as to reduce resistance against AMAs.

Methods : Records of 115 patients of  MICU were evaluated over a period of one year from September 2018 to August 2019.

Results :  24% of prescribed drugs in MICU were AMAs. Average number of AMAs used per patient were 3%. The most commonly prescribed AMAs were Cephalosporins (72%) followed by Amikacin (42%) and Piperacillin/Tazobactam (37%). Out of all prescribed AMAs 74% were from the essential drug list.

Conclusion : There is a need for forming guidelines at local level for rational prescribing of AMAs based on national guidelines. This will further help in preventing antimicrobial resisitance.


Keywords


Prescribing pattern, Antimicrobials, Medical ICU, Cephalosporins

Full Text:

PDF

References


Espasito S, Leone S. Antimicrobial treatment intensive care unit (ICU) infections including the role of infectious diseases specialist. Int J Antimicrob Agents 2007; 29:494-500.

Marin H, Kunches LM, Lichtenberg DA. Comparison of infections in different ICUs within the same hospital. Crit Care Med. 2005;43(2):122-7.

Krishnaswamy K, Dinesh Kumar B,Radhaiah G. A drug survey precepts and practices. Eur J clin pharmacol 1985;29: 363-370

Safadar N, Maki DG. The commonality of risk factors for nosocomial colonization and infection with antimicrobial resistance Staphylococcus aureus, Enterococcus, Gram negative bacilli, Clostridium difficle and Candida. Ann Intern Med 2002; 136:834-44.

Ghanshani R, Gupta R, Gupta BS, Kalra S, Khedar RS, Sood S. Epidemiological study of prevalence, determinants, and outcomes of infections in medical ICU at a Tertiary Care Hospital in India. Lung India 2015; 32:441-8.

Shankar PR, Upadhyay DK, Subish P, Bhandari RB, Das B. Drug utilisation among older inpatients in a teaching hospital in Western Nepal. Singapore Med J. 2010; 51:28–34.

Shankar PR, Partha P, Dubey AK, Mishra P, Deshpande VY. Intensive care unit drug utilization in a teaching hospital in Nepal. Kathmandu Univ Med J (KUMJ) 2005; 3:130–7.

John LJ, Devi P, John J, Guido S. Drug utilization study of antimicrobial agents in medical intensive care unit of a tertiary care hospital. Asian J Pharm Clin Res. 2011; 4:81–4.

Paudel R, Palaian S, Giri B, Hom KC, Sah AK, Poudel A, et al. Clinical profile and drug utilization pattern in an intensive care unit of a teaching hospital in Western Nepal. Arch Pharm Pract. 2011; 2:163–9.

Biswal S, Mishra P, Malhotra S, Puri GD, Pandhi P. Drug utilization pattern in the intensive care unit of a tertiary care hospital. J Clin Pharmacol. 2006; 46: 945–51.

Yamashita SK, Louie M, Simor AE, Rachlis A. Microbiological surveillance and parenteral antibiotic use in a critical care unit. Can J Infect Dis. 2000; 11:107–11.

Inan D, Saba R, Gunseren F, Ongut G, Turhan O, Yalcin AN, et al. Daily antibiotic cost of nosocomial infections in a Turkish university hospital. BMC Infect Dis. 2005; 5:5.

Badar VA, Navale SB. Study of Prescribing Pattern of Antimicrobial Agents in Medicine Intensive Care Unit of a Teaching Hospital in Central India. JAPI April 2012; 60:20-23.


Refbacks

  • There are currently no refbacks.