BACTERIOLOGICAL PROFILE AND ANTIBIOGRAM OF COPD PATIENTS ADMITTED IN TERTIARY CARE HOSPITAL OF NORTH BIHAR

Dr. Amit Prakash, Dr. Prakash Kumar Mishra, Dr. Ranjeet Kumar

Abstract


Introduction : Chronic obstructive  pulmonary disease common is very in smoker and old age . Infection is  common cause of acute exacerbation of COPD. It increases morbidity and day of stay of admitted patients in hospital. Our study purpose is to identify causative microorganism and sensitivity pattern of isolates.

Material &methods : This is retrospective  study, done in  COPD patient  admitted in  hospital . Sputum sample collected  aseptically, culture done on blood agar and Mac Conkey`s  agar.  Positive cases obtained on culture were included in this study. Isolates were identified by standard bacteriological protocol as per CLSI guideline.

Result: Out of 100, 60 bacterial isolates recovered from sputum sample, commonly isolated species are Klebsiella pneumonia, , Staphylococcus aureus ,Pseudomonas spp, E.coli, and Acinetobacter baumanii.

Conclusion: To decrease morbidity and hospital stay in COPD patients, early diagnosis and  initiation of   appropriate treatment of  patients is necessary.


Keywords


Chronic obstructive pulmonary disease (COPD), lung disease, Symptoms, BACTERIOLOGICAL

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References


American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1995;152:S77–S121.

Chhabra SK, Dash DJ. Acute exacerbations of chronic obstructive pulmonary disease: causes and impacts. Indian J Chest Dis Allied Sci. 2014;56(2):93–104.

Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS, the GOLD Scientific Committee. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med 2001;163:1256–1276.

Ferrer M, Alonso J, Morera J, et al. Chronic obstructive pulmonary disease and health related quality of life. Ann Int Med 1997;127:1072–1079.

MacIntyre N, Huang YC. Acute exacerbations and respiratory failure in chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2008;5(4):530–35

Rennard SI, Farmer SG. Exacerbations and progression of disease in asthma and chronic obstructive pulmonary disease. Proc Am Thorac soc. 2004;1:88-92.

Arora N, Daga MK, Mahajan R, Prakash SK, Gupta N. Microbial pattern of acute infective exacerbation of chronic obstructive airway disease in a hospital based study. Indian J Chest Dis Allied Sci. 2001;43:157–62.

Clinical and Laboratory Standards Institute. 2018. Performance standards for antimicrobial susceptibility testing; Twenty first informational supplement. M100- S21. Wayne, PA: CLSI; 2018.

Patel AK, Luhadia AS, Luhadia SK. Sputum Bacteriology and Antibiotic Sensitivity Pattern of Patients Having Acute Exacerbation of COPD in India – A Preliminary Study. J Pulm Respir Med. 2015;5:238.

Miravitlles M, Mayordomo C, Artes M, Sanchez-Agudo L, Nicolau F, Segu JL. Treatment of chronic obstructive pulmonary disease and its exacerbations in general practice. Respir Med. 1999;93:173-9.

Chawla K, Mukhopadhay C, Majumdar M, Bairy I. Bacteriological profile and their antibiogram from cases of acute exacerbations of chronic obstructive pulmonary disease: A hospital based study. Journal of Clinical and Diagnostic Research. 2008;2:612-6.


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