A RARE CASE OF ISOLATED UNPROVOKED DEEP VEIN THROMBOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS

Dr. Kanikalla Nagarjuna, Dr. Rama Lakshmi Thullimalli, Dr. K. Hema

Abstract


A 28-year-old female was admitted in view of sudden onset of painful swelling of right lower limb from 3 days. It was found out to be due to an underlying extensive deep vein thrombosis (DVT) of right lower limb. There was no history suggestive for provocation of thrombosis. So, we further evaluated for the cause of this unprovoked DVT. Upon evaluation we ruled out the inherited thrombophilias like Protein c and s deficiency, Factor V Leiden, Dysfibrinogenemia, etc. Lupus anticoagulant was negative. Interestingly, we screened for Antinuclear Antibody and it came out to be Positive. Later Extractable Nuclear Antigen (ENA) profile revealed significant positivity of Anti Smith Antibodies.

So, we diagnosed this case as a rare case of Systemic Lupus Erythematosus (SLE) presenting as Unprovoked DVT.


Keywords


Systemic Lupus Erythematosus, Deep vein thrombosis.

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References


Cecil Textbook of Medicine, 25th Edition: p:1770, 1774

Ezgi Çoşkun Yenigün, Fatih Dede, Serhan Vahit Pişkinpaşa, Ramazan Öztürk, Nihal Özkayar, Didem Turgut Turk Neph Dial Transpl 2014; 23 (2): 172-174

Lai NS, Lan JL: Renal vein thrombosis in Chinese patients with systemic lupus erythematosus. Ann Rheum Dis 1997; 56(9): 562-564


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