HYPOTENSION ON PRESENTATION AS A PROGNOSTIC FACTOR IN ACUTE CORONARY SYNDROME

Dr. Kaushal V. Sheth, Dr. Pooja A. Halani, Dr. Prakash V. Makwana

Abstract


INTRODUCTION: Coronary heart disease (CHD) is the major cause of death in developing countries like India. Acute Myocardial Infarction
(AMI) is the most important form of CHD. Cardiogenic Shock (CS) is a dreaded clinical condition with a high mortality rate of 50 - 80% in patients
of CS due to acute myocardial infarction. It is an established fact that inpatients with CS, complicating acuteMI, one year survival is better in those
receiving early revascularisation versus initial medical stabilization; however, data demonstrating longterm survival was lacking.
METHODOLOGY: 60 Cases of Acute Coronary Syndrome (ACS) presented as cardiogenic shock and 60 patients with Acute coronary
Syndrome (ACS) without shock admitted in GGH from September 2015 to September 2016.
RESULTS: In present study majority of patients presented with anterior wall MI (33% in MI without CS group; 41% in MI with CS group). overall
incidence of ventricular tachycardia was 22.5% as compared to retrospective study incidence of arrhythmias (13% to 19%). Elderly age, Obesity,
Delayed presentation to hospital, Past history of IHD , High TIMI risk score on presentation and unsuccessful thrombolysis drastically increase the
risk of cardiogenic shock in patients with M.I. Incidence of mortality in present study is 13.33% in MI without CS group and 68.33% in MI with CS
group, which directly states that cardiogenic shock is strongest predictive risk factor for patients of MI.


Keywords


Cardiogenic Shock, Acute Coronary Syndrome, Myocardial Infarction

Full Text:

PDF

References


Goldeberg JR,Samad NA etal studies incidence of CS was highest in anterior wall MI i.e.

33% in our study, 71% in Gupta MS et al, 58% in Berham M et al and 44% in Grag K

C et al study. .Temporal trends in cardiogenic shock complicating acute myocardial

infarction. The NEJM; 1999;1162-68.

L. Khalid, S.H. Dhakkam. A Review of Cardiogenic Shock in Acute Myocardial

Infarction. Current ischemic heart disease, In: Hurst’s Cardiology Reviews, 2008, 4, 34-

Konstantina Bouki, George Pavlakis, Evangelos Papasteriadis. Cardiogenic Shock

Complicating Acute Coronary Syndromes. Hellenic J Cardiol 44: 392-399, 2003.

Holmes DR, Berger DP et al. Cardiogenic Shock in Patients With Acute

IschemicSyndromes With and Without ST-Segment Elevation. Circulation.

;100:2067-2073.

Wadhwa S. Cardiogenic Shock- Current status. JIACM 2007; 8(2): 146-9.

Sethi KK., ed “Preface” in Coronary Artery Disease in Indians. A Global Prospective

: 9 pp.

Wenger N.K: Coronory heart disease and women, magnitude of problem. Cardial Rev.

:211,2002

Kannel WB : The Framingham study: historical insight on the impact of cardiovascular

risk factors in men versus women : J. Gend Specif MED 5:27, 2002

Schlant RC, Alexander RW, editors. Diagnosis and management of chronic The Heart:

thed. New York: McGraw Hill; Inc. 1994, 1055 pp.

Prandfit origin of concepts of IHD.BMJ, 50: 209, 1983.

Cardiovascular disease. (2006). Encyclopedia Britannica. Retrieved January 20, 2006,

from Encyclopedia Britannica Premium Service

Julian DG. Treatment of cardiac arrest in acute myocardial ischaemia and infarction;

Lancet 1961;11:840-4.

Stanek V, Progress in the therapy of ischemic heart d i s e a s e , K a p i t o l y z k a r d i

ologie2002;4:3-11.

Mehta NJ, Khan IA. Cardiology’s 10 greatest discoveries of the 20thcentury; Tex Heart

Inst J 2002; 29: 164-71.

Braunwald E. The Simon Dacklecture. Cardiology: The past, the present, and the future.

J Am Col Cardiology 2003;42:2031-41.


Refbacks

  • There are currently no refbacks.