STUDY OF PRESCRIPTION PATTERN IN PAEDIATRIC PATIENTS OF BRONCHIAL ASTHMA ATTENDING OUT PATIENT DEPARTMENT IN A TERTIARY CARE TEACHING HOSPITAL

Sukhmeen Kaur, Bhagya. M. Sattigeri, Deepali Jaybhaye, Shruti Chandra

Abstract


Background of the study: Pediatric bronchial asthma is a common chronic airway disorder which requires long term management. Globally, irrational prescribing poses a huge problem which increases the cost of treatment as well as incidence of adverse drug reactions. This emphasizes dire necessity for monitoring of prescriptions pattern. As such, this study was planned.

Materials and Methods: An observational, non-interventional, and cross-sectional study was conducted in a tertiary care teaching hospital in Aurangabad. All childhood asthma patients attending outpatient department were enrolled in the study in accordance with inclusion and exclusion criteria. Patient’s demographic details, details of anti-asthmatic drugs, and all other drugs such as dose, duration, type of dosage form used, frequency of drug administration, etc. were recorded.

Results: Out of 300 children enrolled in the study, majority were males and belonged to the age group of 6-10 years. 43.67% patients received single anti-asthmatic drug whereas, 56.34% patients received multiple drug therapy. Average number of drugs per prescription was 2.89. Inhalational route was preferred and all the drugs were prescribed by their brand names. Short acting beta 2 agonists (85%) was prescribed the most followed by (47.66%) inhalational corticosteroids. Antibiotics were prescribed in 11.33% patients.

Conclusion: Prescribing trends in anti-asthmatic drugs were mainly in accordance with the standard treatment guidelines. However, all the drugs were prescribed by brand names. To overcome this, training should be provided to health care practitioners regarding WHO drug policies and significance of generic prescribing.


Keywords


Bronchial asthma, Prescription pattern, Anti asthmatic drugs

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References


Herzog R, Rundles SC. Paediatric asthma: natural history, assessment and treatment. Mt Sinai J Med. 2011; 78(5): 645–660. doi:10.1002/msj.20285.

Lee-Sarwar KA, Bacharier LB, Litonjua AA. Strategies to alter the natural history of childhood asthma. Curr Opin Allergy Clin Immunol 2017; 17:139-45.

Bahadori K, Doyle-Waters MM, Marra C, Lynd L, Alasaly K, Swiston J, et al. Economic burden of asthma: a systematic review. BMC Pulm Med 2009; 9:24.

Braman SS. The global burden of asthma. Chest. 2006;130 1 Suppl:4S-12.

Global Initiative for Asthma: Global strategy for asthma management and prevention. online appendix. 2018. http://www.ginaasthma.com

International study of Bronchial Asthma and allergies in childhood (ISAAC). Worldwide variations in the prevalence of Bronchial Asthma symptoms. Euro Respir J 1998; 12:315-35.

Pal R, Dahal S, Pal S. Prevalence of bronchial asthma in Indian children. Indian J Community Med. 2009; 34:310-6.

Tundia MN, Thakrar DV. An epidemiological study of asthma and its risk factors in school going children in Bhavnagar city, Gujarat, India. Int J Community Med Public Health. 2018 Jun;5 (6): 2317-2322.

Sun HL, Kao YH, Chou MC, Lu TH, Lue KH. Differences in the prescription patterns of anti-asthmatic medications for children by paediatricians, family physicians and physicians of other specialties. J Formos Med Assoc. 2006 Apr; 105(4):277-83.

Batta A, Madan N, Kalra BS, Arora S. Prescription Audit, Drug Utilization Pattern and Adverse Drug Reaction Monitoring in Outpatients of Orthopedics Department of Tertiary Care Teaching Hospital: A Pilot Study. MAMC J Med Sci 2019; 5:77-82.

Spreight A, Lee D, Hey E. Under diagnosis and under treatment of asthma in childhood. Br Med J 1983; 286:1253-6.

Karande S, Sankhe P, Kulkarni M. Patterns of prescription and drug dispensing. Indian J Pediatr 2005, 72:117–121.

Sol IS, Kim YH, Kim SY, Choi SH, Kim JD, Kim BO, et al. Prescription patterns and burden of pediatric asthma in Korea. Allergy Asthma Immunol Res 2019; 11:280–290.

National Heart, Lung, and Blood Institute, National Institutes of Health. International Consensus Report on the Diagnosis and Treatment of Asthma. Bethesda: National Heart, Lung, and Blood Institute, National Institutes of Health, March 1992. Publication no. 92-3091.

NIH. Guidelines for the Diagnosis and Management of Asthma. Bethesda: National Institutes of Health (NIH), May 1997. p. 41 Publication no. 97-4051 A.

National Heart, Lung and Blood Institute, WHO. Global Strategy for Asthma Management and Prevention. Bethesda: NHLBI/WHO workshop, 1997. NIH Publication no. 974051.

GINA Reports - Global Initiative for Asthma - GINA [Internet]. Global Initiative for Asthma - GINA. 2019 Available from: https://ginasthma.org/gina-reports/

Garje YA, Suman RK, Kumar R, Deshmukh YA, Patra V. Prescribing patterns and pharmacoeconomic analysis of drugs used in paediatric asthma patients at tertiary care hospital. World J of pharm pharmaceutical sci. 2014; 3(6), 1448-1465.

Gupta MK, Patodia J, Chaudhary P, Kakkar M. The rising trend of asthma prevalence in urban school children of Jaipur: A questionnaire-based study. Indian J Allergy Asthma Immunol 2018; 32:10-4.

Gershon AS, Wang C, Guan J, To T. Burden of comorbidity in individuals with asthma. Thorax. 2010;65(7):612–618.

Valerio MA, Andreski PM, Schoeni RF, McGonagle KA. Examining the association between childhood asthma and parent and grandparent asthma status: implications for practice. Clin Pediatr (Phila). 2010; 49(6):535–541.

Xu D, Wang Y, Chen Z, et al. Prevalence and risk factors for asthma among children aged 0-14 years in Hangzhou: a cross-sectional survey. Respir Res. 2016;17(1):122.

Gupta S, Awasthi S. Assessment of treatment pattern of childhood asthma reporting to outpatients’ facility of a tertiary care hospital in Lucknow, North India: A cross-sectional study. Clinical Epidemiology and Global Health. 2016; 4: S6-S11.

Kumar V, Thankachan T, Amanapu A, Chandra D, Krishnan S. Study of Prescribing Pattern and Impact of Pharmaceutical Care in Bronchial Asthmatic Paediatric Patients in a Tertiary Care Teaching Hospital. Indian Journal of Pharmacy Practice. 2015; 8(1):42-48.

Karki S, Mohanty I R, Potdar PV, Deshmukh YA, Shah RC, Pokhrel BR. Assessment of prescribing patterns of drugs used in adult asthma patients at a tertiary care hospital. Int. J. Curr. Res. Med. Sci. 2017; 3(6): 169-175.

Pandey A, Tripathi P, Pandey R. Prescription pattern in asthma therapy at Gorakhpur hospitals. Lung India. 2010;27(1):8.

Shimpi RD, Bavaskar R, Laddha GP, Kalam A. Patel K. Drug utilization evaluation and prescription monitoring in asthmatic patients. Int J Pham Bio Sci. 2012; 2:117-22.

Prasad A, Pradhan S, Datta P, Samajdar S, Panda P. Drug prescription pattern for bronchial asthma in a tertiary-care hospital in Eastern India. National Journal of Physiology, Pharmacy and Pharmacology. 2015; 5(3): 263.

NAEPP Expert Panel Report: guidelines for the diagnosis and management of asthma updates on selected topics 2007. Available from: http://www.nhlbi.nih.gov/guidelines/asthma

Rafeeq MM, Murad H. Evaluation of drug utilization pattern for patients of bronchial asthma in a government hospital of Saudi Arabia. Niger J Clin Pract. 2017; 20:1098-105.

Patel Pinal D, Patel RK, Patel NJ; Analysis of Prescription Pattern and Drug Utilization in asthma Therapy; International Research Journal of Pharmacy. 2012; 257-260.

Robertson C, Price D, Henry R, Mellis C, Glasgow N, Fitzgerald D et al. Short-Course Montelukast for Intermittent Asthma in Children. American Journal of Respiratory and Critical Care Medicine. 2007;175(4):323-329.


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