COMPARATIVE STUDY OF CONVENTIONAL URINE CYTOLOGY VERSUS THE PARIS SYSTEM WITH HISTOLOGIC CORRELATION : A SINGLE INSTITUTIONAL STUDY OF 120 CASES.

Dr Muktanjalee Deka, Dr Bonita Borah

Abstract


Background: Urine cytology continues to be an important test for screening,diagnosis and monitoring of patient with urothelial carcinoma.It is
more specific for High grade urothelial cancers(HGUC) .Our objective is to compare the performance of The Paris System for Reporting Urine
Cytology with our institutional reporting system.
Materials and Methods :A cross sectional observational study was conducted over a period of one year from June 2018 to May 2019. A total of
315 urine specimen was studied from 120 patients who presented with hematuria and other urinary tract symptoms to the Department of Urology.
Cytological diagnosis was done by both The Paris System(TPS) and original institutional reporting system(ORS) and correlated with gold
standard histology.
Results and Observation: More cases were found to be under Negative for High Grade Urothelial Carcinoma (NHGUC) i.e. 37% by TPS VS 23% by
ORS, lower number of cases assigned as atypical category (AUC) using TPS ( 25% by TPS VS 39% by ORS),with regards to AUC category 56% cases
were subsequently diagnosed as HGUC using TPS compared to 26% by institutional reposting system. There was minimal difference in
performance of suspicious for high grade urothelial carcinoma (SHGUC) / high grade urothelial carcinoma (HGUC) using both the system .
Conclusion: The Paris System of reporting urine cytology has improved the performance of urine cytology by targeting the diagnosis of HGUC
which is clinically significant.


Keywords


urine cytology , the Paris System for reporting urine cytology, urothelial carcinoma

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References


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