A CROSS-SECTIONAL STUDY TO STUDY THE ASSOCIATION OF VITAMIN D LEVELS WITH GLYCOSYLATED HEMOGLOBIN LEVELS IN ELDERLY OF BANGALORE CITY

Dr. Jyothi Vybhavi V. S.

Abstract


BACKGROUND: Ageing is a natural process and healthy ageing has become a growing global challenge. The process of ageing affects
nutritional needs, they are particularly prone to inadequate intake of VitaminD. Vitamin D is suggested to influence glucose homeostasis. An
inverse relationship between serum 25‐hydroxyvitamin D (25[OH]D) and glycemic control with type 2 diabetes was reported in previous studies.
Hence this study was undertaken to investigate the association between vitamin D and Glycosated Hemoglobin levels in elderly of Bangalore city.
OBJECTIVES: A. To estimate Serum Vitamin D levels in the elderly. B. To estimate Glycated Hemoglobin Levels in the elderly C. To correlate
the Vitamin D levels with Glycosylated Hemoglobin Levels in the elderly of Bangalore city.
METHODOLGY: This study involved 80 healthy elderly subjects with consideration of inclusion and exclusion criteria. Written informed
consent was taken. For each subject, fasting blood sample of 4ml was collected for Serum 25(OH) Vitamin-D assessment and Glycosylated
Hemoglobin levels. Anthropometric measurements were taken. 24-hour dietary recall, General history questionnaire were administered. Results
were compiled and statistically analyzed.
RESULTS: Serum 25(OH)D levels were inversely associated with A1C levels. These results are after adjusting for age, sex, A1C, BMI, treatment
and duration of diabetes.
CONCLUSION: It can be concluded that Low Serum Vitamin D levels were associated with higher Glycosalated Hemoglobin levels warranting
the need for educating the senior citizens the importance of Vitamin D and its supplementation for a Healthy Ageing.


Keywords


Vitamin D, Diabetes Mellitus, Hemoglobin A1c, Glycemic Control

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