ROLE OF MEAN PLATELET VOLUME (MPV) IN ASSESSING THE SEVERITY OF DENGUE.

Dr Talatnoor Sheikh, Dr Shilpi Sahu

Abstract


Background: Dengue is common viral infection which is has seasonal outbreak and has big burden on the health sector in our country. The patients
presents with fever, arthralgia, malaise along with other symptoms in case of dengue haemorrhagic fever. The patients have thrombocytopenia
along with leucopenia. Recently lot of importance has been given to platelet indices for assessing severity of dengue infection. Aim was to study the
significance of mean platelet volume (MPV) is assessing the severity of dengue infection.
Methods: The present study is a prospective observational study conducted in a tertiary hospital in Navi Mumbai among 300 patients positive for
dengue fever with thrombocytopenia. Their complete hemogram was performed and MPV was compared with the platelet count. Categorical data
were presented as numbers (percent) and were compared among groups using Chi-square test. Groups compared for demographic data were
presented as mean and standard deviation and were compared using student t-test using SPSS, version 20 for Windows. P value of <0.05 was
statistically significant
Results: The most common clinical feature in patients with dengue after fever was Arthralgia 73.2 %. NS1 was positive in 71% of the cases. 41%
patients had platelet count between 50,000-1 lac. The mean MPV was 7.28 fl and total leucocyte count 3446 cells/cumm.
Conclusion: The mean platelet volume decreases with decrease in platelet count observed in dengue fever, which can help in predicting the
severity of dengue infection.


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