Lt Col Dhanalakshmi B


Breast cancer is a leading cause of cancer mortality among women with 12.5% lifetime risk for developing breast cancer by 85 years of age (1). The
incidence is also increased by about 4% per year since 1980's. However Surveillance, Epidemiology, and End Results (SEER) programme
reported decrease in the breast cancer mortality rate from 3.1 % to 9.3 % during the period of 1989 to 1992 across all age groups.(2) This decrease in
mortality was at least partially attributable to the benefits gained by early detection through screening mammography. The high prevalence and
need for early treatment of breast malignancy emphasizes the need for early and accurate diagnosis.
The radiological examination of breast is an integral part of modern multidisciplinary approach for effective management of breast disease (3). The
aim of breast imaging is to assess the probability of a lesion being benign or malignant. Currently digital mammography, ultrasound, color Doppler
and MRI are being utilized for detection of breast cancer.
The suspicious lesion has to be evaluated with tissue diagnosis as well as MRI as the MRI has advantage of evaluation of whole breast with dynamic
curve and diffusion weighted imaging, if needed spectroscopic evaluation.


CAD - Computer aided detection, DCEMRI - Dynamic contrast enhanced Magnetic Resonance Imaging, Gd-DTPA - Gadolinium diethylenetriamine pentacaetic acid, MRI - Magnetic resonance imaging, Mammo - Mammography, PPV - Positive predictive value, PET - Positive

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