CHARACTERIZATION OF SLEEP QUALITY IN VITAMIN D DEFICIENT ELDERLY OF BANGALORE CITY

Dr. Jyothi Vybhavi V. S

Abstract


The older population is at a high risk of Vitamin-D deficiency due to decreased cutaneous synthesis and dietary intake of Vitamin-D. Although recent studies have investigated the influence of Vitamin-D on sleep patterns, there is a lack of research on the relationship between Vitamin-D and sleep patterns in elderly population. Hence there is a need to evaluate whether Vitamin-D deficiency affects sleep quality in the elderly. Objectives: A.                To assess Serum 25(OH) Vitamin-D in the elderly. B.           To assess Sleep Quality in the elderly with different levels of Vitamin-D. Material & Methods: This study involved 80 healthy elderly subjects with consideration of inclusion and exclusion criteria. Written informed consent was taken. For each subject, fasting blood sample of 4ml was collected for Serum 25(OH) Vitamin-D assessment. Anthropometric measurements were taken. 24-hour dietary recall, General History Questionnaire using the Pittsburgh Sleep Quality Index were administered and quality of sleep was evaluated. Results were compiled and statistically analyzed. Results: A comparison of Serum Vitamin-D levels and PSQI components showed that the mean scores for subjective sleep duration, sleep latency, and sleep quality were significantly higher in the Vitamin-D deficient participants, indicating that the Vitamin-D deficient participants had poorer sleep quality. Conclusion: A significant correlation was found between Serum Vitamin-D deficiency and poor sleep quality. Based on the results of this study, sleep disorder management for elderly can be improved by providing regular examinations checking their Serum Vitamin-D levels and supplementing Vitamin-D to the elderly to enhance their quality of sleep.

 


Keywords


Vitamin-D, Sleep quality

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References


Caruso LB,Silliman RA. Harrison's Principles of Internal medicine. 17th ed. USA:McGraw Hill;2008.p. 53-62.

Park.k. Park's Textbook of Preventive and Social Medicine. 22nd ed.NewDelhi:Bhanot;2008.p.408

Jeyalakshmi S,Chakrabarti S,Gupta N. Situation Analysis of The Elderly in India. New Delhi:Central Statistics office,Ministry of statistics & Programme Implementation.Government of India; 2012

United Nations Population Fund. Elderly to constitute 20 percent of India’s population by 2050: Report. New Delhi; 2012

Hirshkowitz M. National Sleep Foundation's sleep time duration recommendations: methodology and results summary. Sleep Health. 2015 Mar;1(1):40-43

Gominak SC, Stumpf WE. The world epidemic of sleep disorders is linked to vitamin D deficiency. Med Hypotheses. 2012;79:132–5.

Lee J, Lee JS, Park SH, Shin SA, Kim K. Cohort Profile: The National Health Insurance Service–National Sample Cohort (NHIS-NSC), South Korea. Int J Epidemiol. 2016;dyv319.

Lee HJ, Lee HD, Hwang HS, Park HK, Kim SE. Associations between Serum Vitamin D Level and Mean Hours of Sleep: 2011 Korea National Health and Nutrition Examination. Survey Korean J Fam Pract. 2014;4:293–8.

Norman AW, Bouillon R. Vitamin D nutritional policy needs a vision for the future. Exp Biol Med. 2010;235:1034–45.

Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh sleep quality index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193–213.

Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF.Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr. 2000 Sep;72(3):690-3.

Body Mass Index.[Internet] 2015[ cited 2015 May 2015] Available from: http://www.euro.who.int/en/health-topics/disease-prevention/nutrition/a-healthy-lifestyle/body-mass-index-bmi

Fradinger EE, Zanchetta JR.Vitamin D and bone mineral density in ambulatory women living in Buenos Aires, Argentina. Osteoporosis Int. 2001;12:24-7.

Holick MF Siris E, Binkley N. Prevalence of Vitaamin D inadequacy among postmenopausal North American women recieving osteoporosis therapy. J Clin Endocrinol metab. 2005;90:3215-24.

Holick MF. The Vitamin D deficiency pandemic: a forgotten hormone. Public health reviews. 2010;32:267-83.

Holick MF.. Vitamin D : A delightful solution for health. J Investig Med. 2011;59(6):872-80.

Maclaughlin J A, Holick M F. Aging decreases the capacity of human skin to produce Vitamin D3. Journal of clinical investigation. 1985;76:1536-8.

Omdahl JL. Nutritional status in a healthy elderly population:Vitamin D. The American journal of clinical nutrition. 1982;36:1225-33.

Fleet Jc. Molecular Mechanisms for Regulation of intestinal Calcium absorption by Vitamin D and other factors. Crit Rev Clin Lab sci. 2010;47(4):181-95.

Jennifer M, Katie L, Esther K, Stephanie L, Elizabeth BC, Nancy E, et al. Vitamin D and Actigraphic Sleep Outcomes in Older Community-Dwelling Men: The MrOS Sleep Study. Sleep. 2015;38(2):251–7.

Gominak SC, Stumpf WE. The world epidemic of sleep disorders is linked to vitamin D deficiency. Med Hypotheses. 2012;79:132–5.

Stumpf WE, Jennes L. The A-B-C (Allocortex-Brainstem-Core) circuitry of endocrine-autonomic integration and regulation: aproposed hypothesis on the anatomical-functional relationshipsbetween estradiol sites of action and peptidergic-aminergicneuronal systems. Peptides. 1984;5(Suppl 1):221–6.


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