N. G. Tamil Selvi, D. Nagarajan, S. Sridevi


The zebra fish (Danio rerio) has proven an excellent model for the study of vertebrate development and genetics. Mutagenesis studies have produced many blood mutants with defects ranging from haematopoisis to coagulation.  The over helming majority of zebra fish studies  have focused on development and mutation effects in embryos, whereas effects in mature zebra fish have gone largely unexplored.  Zebra fish will prove a valuable model for studying of ageing and age related diseases and we have sought to characterize some of the basic features of mature zebra fish. Accordingly, blood was collected from adult zebra fish and was analyzed to determine the hematological parameters. Hematological parameters are important for toxicological research environmental monitoring and as indicators of disease and environmental stress). Blood is known to exhibit pathological changes before the onset of any external symptoms of toxicity Zebrafish have contributed to hematological research for more than 100 years. Interest in zebrafish embryology and they have long used for toxicology and other zoological research. We believe results such as these will help define normal adult zebra fish, which have a tremendous potential for use in the study of human disease, hematological disorders and aging.


Zebrafish, haematopoisis, toxicological, triclosan.

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