Dr. Chetna Ashok Shamkuwar, Dr. Nalini Kumari, Dr. Sushant H. Meshram


The incidence of CKD is increasing and there are very few studies of medication prescribing pattern in Haemodialysis patients in central India, hence the  present study was planned  to evaluate the  medication prescribing pattern in CKD patients on haemodialysis.

Methodology: An observational study with prospective design was conducted in the department of Nephrology in a superspeciality tertiary care teaching hospital from May 2011 to May 2012 and a total hundred and twenty (120) patients were enrolled after written informed consent of each patient. 

Results: Out of 120 patients of CKD undergoing hemodialysis, 95 were males and 25 were females with a mean age of 41.37 ± 13.25.  Most common co-morbid condition associated with CKD was hypertension (92) followed by anemia (50). A total of 1926 drugs were prescribed off which only 285 drugs were prescribed by generic name. a total of 15 patients died out of 75 patients which were prescribed between 8-15 drugs about 12 patients died (9%).


CKD, Hemodialysis, Prescribing patterns.

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Ruggenenti P, Schieppati A, Remuzzi G: Progression, remission, regression of chronic renal diseases. Lancet 2001, 357(9268):1601-8.

Modi GK, Jha V: The incidence of end-stage renal disease in India: a population-based study. Kidney Int 2006, 70(12):2131-3.

National Kidney Foundation. KDOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Am J Kidney Dis 2002;39:S1-266

Jha V, Garcia-Garcia G, Iseki K, Li Z, Naicker S, Plattner B, et al. Chronic kidney disease: Global dimension and perspectives. Lancet. 2013;382:260–72.

Kappel J, Calissi P. Safe drug prescribing for patients with renal insufficiency. Can Med Assoc J 2002; 166: 473-7.

.Gubardi S, Ambrason S. Drug dosing in chronic kidney disease. Med Clin North Am 2005; 89: 649-87

Rama M, Viswanathan G, Acharya LD, Attur RP, Reddy PN, Raghavan SV. Assessment of Drug-Drug Interactions among Renal Failure Patients of Nephrology Ward in a South Indian Tertiary Care Hospital. Indian J Pharm Sci 2012;74:63-85.

Bailie GR, Eisele G,Liu L, Patterns of medication use in the RRI-CKD study: focus on medications with cardiovascular effects. Nephrol Dial Tranplant 2005;20:1110-1115.

Chiu YW, Teitelbaum I, Misra M, Pill burden, adherence, hyperphosphatemia, and quality of life in maintenance dialysis patients. Clin J Am Soc Nephrol 2009;4:1089-1096.

Kanakambal S; Murgesh N; Shanthi M. Drug prescribing pattern in a tertiary care hospital in Madurai. Ind J Pharmacol; 2001; 33, 223

WHO collaborating Centre for Drug Statistics Methodology. Anatomic-therapeutic-chemical classification of drugs (ATC) Classification index. Norway: 2005. Available from http://www.whocc.no/atcddd.

Jonathan Himmelfarb, M.D., T. Alp Ikizler, M.D. Hemodialysis, N Engl J Med 2010; 363:1833-1845.

Manley HJ, Garvin CG, Drayer DK, et al. Medication prescribing patterns in ambulatory haemodialysis patients: comparisons of USRDS to a large not-for-profit dialysis provider. Nephrol Dial Transplant 2004;19: 1842-8.

Bajait CS, Pimpalkhute SA, Sontakke SD, Jaiswal KM, Dawri AV. Prescribing pattern of medicines in chronic kidney disease with emphasis on phosphate binders. Indian J Pharmacol 2014;46:35-9.

Tamilselvan T, Veerapandiyan AK, Karthik N. Study on drug utilization pattern of chronic renal failure patients in a tertiary care hospital. Hypertension 2014;70:112.

Goodman WG, Quaries LD, Development and progression of secondary hyperparathyroidism in chronic kidney disease: lesson from molecular genetics; Kidney Int. 2008 Aug;74 (3);276:88.

Curtin RB, Svarstad BL, Keller TH (1999) Hemodialysis patients' noncompliance with oral medications. Anna J 26: 307–316; discussion 317:35.

Reilly R F, Jackson E K, Weitz J I, Dandan R H, etal. Modulation of cardiovascular function. Goodman and Gillman’s the pharmacological basis of therapeutics. 12th edition; 669-908.

Bishu K, Gricz KM, Chewaka S, Agarwal R.Appropriateness of Antihypertensive Drug Therapy in Hemodialysis Patients. Clin J Am Soc Nephrol 2006; 1: 820–24.


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