PREVALENCE AND CLINICAL FEATURES OF CRYPTOCOCCAL MENINGITIS IN HIV SERO-POSITIVE PATIENTS : ORIGINAL REASERCH STUDY IN TERTIARY CARE HOSPITAL.

Dr. Aparna Gaini, Dr. Hema Kumari. E, Dr. B. Srinivasa Rao

Abstract


Aim: To find out the prevalence & clinical features of Cryptococcus neoformans in CSF causing meningitis in HIV seropositive patients and other bacterial pathogens in CSF causing meningitis in HIV seropositive patients.

Methods: This Study was undertaken in Government General Hospital , VJA during July 2018 to March 2016.Total 50 HIV sero-positive patients who presented with the clinical features suggestive of meningitis and low CD4 count were screened for cryptococcal meningitis.

Results: In present study amongst 50 cases, 4 cases (8%) were positive for Cryptococcus neoformans and 46 cases (92%) were negative for Cryptococcus neoformans.

Conclusion: cryptococcal infections should be suspected in all cases of meningitis among HIV seropositive patients as early diagnosis of paramount importance for better management of such patients.


Keywords


Opportunistic infections; Cryptococcus neoformans; meningitis; HIV seropositive; CD4 count

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References


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