A COMPARATIVE STUDY OF FENTANYL AND NALBUPHINE ON HAEMODYNAMIC CHANGES DURING INTUBATION IN GERIATRIC PATIENTS

Dr Sk Ahadul Islam, Dr Sujata Dalai

Abstract


Objective: The haemodynamic changes associated with laryngoscopy and endotracheal intubation are due to mainly sympathoadrenal reflex and release of norepinephrine, epinephrine.  So, laryngoscopy and intubation is a challenge to anaesthesiologist with obtundation of pressor response in these patients.

Methods: Seventy patients were randomly selected matching the inclusion criteria and they were randomly allocated in either of two groups (n=35).  Group F was given i.v. fentanyl 2mcg/kg and group N given i.v. Nalbuphine 0.2 mg/kg five min before intubation.  we excluded the patient whose laryngoscope and intubation time was exceeded 15 secs.

Results:  The  SBP and DBP,MAP and mean heart rate of the patients of group-N was significantly higher than that of group-F after drug administration to 5 minute after intubation (p<0.01). 

Conclusion: Intravenous fentanyl (2mcg/kg) controls the stress response to laryngoscopy and intubation  better as compared to i.v nalbuphine (0.2mcg/kg) in geriatric patients but the adverse effect profiles are more in fentanyl arm.


Keywords


Geriatric, laryngoscopy and intubation, fentanyl, nalbuphine.

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References


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