A PROSPECTIVE INTERVENTIONAL STUDY TO ASSESS THE CLINICAL EFFICACY OF VISCO-SUPPLEMENTATION ON KNEE OSTEOARTHRITIS IN A TERTIARY CARE CENTER OF NEW DELHI

Dr Jaydeep Nandi, Dr S Y Kothari, Dr Rajendra Sharma

Abstract


Osteoarthritis, also known as degenerative joint disease, is the most common type of musculoskeletal disease and is a leading cause of disability among the elderly. In our present study we have included symptomatic primary OA knee patients and treated them with 3 intra articular doses of high molecular weight sodium hyaluronic acid. It was found that the intake of rescue analgesic (paracetamol) as well as the supra-patellar circumference has decreased in between baseline and other follow up visits (45, 90 and 180 days) but the effect diminished in between the 3rd and 4th follow up. Similarly, there was significant improvement in fifty feet walking time from baseline to other subsequent visits but the entire gain in walking speed was within the first 45 days. The Health Assessment Questionnaire (HAQ), published in 1980 by the Stanford Arthritis Center, is among the first patient reported outcome (PRO) instruments and is also the most cited and employed PRO instruments till date, particularly but not exclusively in the rheumatic disease literature. As before there is significant decrease in HAQ score from baseline to all other subsequent visits, but there is a plateauing of effect in between 3-6 month.


Keywords


Osteoarthritis, patient reported outcome (PRO), musculoskeletal disease

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References


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