Dr. Anubha, Dr. Ranjeet Kumar, Dr. R. N. Sharma


BACKGROUND & OBJECTIVES: HIV, HBV and syphilis in pregnancy are associated with adverse pregnancy
outcomes including spontaneous abortion preterm birth still birth low birth weight, congenital infections etc. The present
study was undertaken to know the sero-prevalence of HIV, HBV and syphilis in and around MUZAFFARPUR.
METHODS: The study was conducted in the Department of Microbiology, S.K MEDICAL COLLEGE, MUZAFFARUR from May 2018 to
April 2019. The study included 300 blood samples of antenatal women attending outpatient and inpatient department of OBSTETRICS AND
GYNAECOLOGY and also private hospital antenatal cases, whose blood samples were sent for routine blood investigations to our Laboratory
All the test sera were tested for and-HIV IgG antibodies by a DOT immunoassay, if reactive was conrmed by TRIDOT and ELISA test. They
were also tested for HBV by HBsAg ELISA and syphilis by VDRL test, if reactive was conrmed by TPHA test
RESULTS: Out of 300 antenatal cases, 3 were positive for HIV i.e. prevalence of 1%, 5 were positive for HbsAg i.e. prevalence of 1.7%, 1 was
positive for anti-treponemal antibodies i.e. prevalence of syphilis was 0.3%.
CONCLUSION: Prevalence of HIV, HBV are high from this study, so it is important to screen all the anterata) mothers for both, so as to provide
proper antenatal, intranatal and post natal care to seropositive women and prevent MTCT. Eventhough the seroprevalence of syphilis is low from
the present study, it is advisable to screen for syphilis also as the disease is treatable and thus helps to eliminate the adverse effect of untreated
syphilis both in mother and foetus.


Hiv; Hbv; Syphilis: Seroprevalence; Elisa: Triot, Dot Immunoassay, Vdrl: Tpha.

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