DOES BACTERIAL BIOFILM AFFECT QUALITY OF LIFE AND PROGNOSIS IN PATIENTS OF CHRONIC RHINOSINUSITIS ?
Abstract
Aims: - To assess the presence of bacterial biolm on the sinus mucosa of chronic rhinosinusitis (CRS) patients and to
evaluate the relationship between biolm and clinical features of CRS.
Methods and Material: – It is a prospective study carried out on 100 patients. Samples of diseased paranasal sinus mucosa with CRS who
underwent functional endoscopic sinus surgery were analyzed with tube method to detect bacterial biolm.
Results: Bacterial bio lm was observed in 29 out of 50 (58%) disease group cases and 3 out of 50 (6%) control group , (p <0.001).The average
Lund Mackay score and symptom score and preoperative Lund Kennedy endoscopic score were signicantly higher in biolm positive than bio
lm negative patients.
Conclusions: This study demonstrates bio lm, a possible cause for the persistent inammation, antibiotics resistance and clinical characteristics
of CRS patients. Bio lm delays healing process in CRS patients.
Keywords
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