Dr. Sushma Cherukuru


Background:  The gastroduodenoscopy and biopsy is the diagnostic tool of choice to detect gastroduodenal diseases. However, endoscopic diagnosis is not always predictive of microscopic findings.

Objective: To study varied spectrum of histopathological lesions both non-neoplastic and neoplastic in patients undergoing gastroduodenal biopsy.

Materials and Methods: This is a prospective study of 100 patients with gastroduodenal diseases who underwent gastroduodenoscopy from December 2014 to June 2016.

Results: In our study, the majority of patients were between 34 to 62 years, with male predominance (49.28%). Chronic gastritis (44%) was most common followed by gastric adenocarcinoma (15%) (intestinal type-80%); diffuse type-20%), and chronic duodenitis (15%). A rare case of granulomatous gastritis and ampullary carcinoma was found.

Conclusion: Non neoplastic lesions were more common than the neoplastic lesions. The gross findings on endoscopy are not disease specific. Histopathological study of biopsy specimen will confirm endoscopic diagnosis in most of the cases.



Gastroduodenal; Histopathology; Granulomatous; Ampullary; Adenocarcinoma.

Full Text:



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