Dr Seema Rani, Dr Niharika Dixit, Dr Devika choudhry, Dr P. K. Sharma


Introduction: Causes of chronic urticaria (CU) remain obscure. Laboratory parameters or biomarkers
can be a predictor of duration and severity of Urticaria.
Objective: The aim of this study was to evaluate the association between clinical parameters of chronic urticaria and various
Methods: A retrospective cross-sectional data of 134 patients of chronic urticaria seen in allergy-clinic, during recent 2 years
span were collected. Demographic details, duration of the disease, urticaria activity score (UAS), Autologus serum skin test
(ASST) and various autoimmune and inammatory laboratory parameters were included.
Results: We found disease activity (UAS) was signicantly associated with biomarkers, ASST (.044), CRP (.025) and ANA (.000).
ANA positivity was signicantly (.000) associated with duration of the disease.
Conclusions: The present study found association of chronic urticaria with inammatory and autoimmune markers; hence it is
important to monitor certain laboratory testings like, CRP, ESR, ANA, ASST, Thyroid auto antibodies, IgE and routine blood
count to predict the disease duration, severity and to manage patients appropriately


Urticaria; biomarkers; Autoimmunity; Inammatory

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