STUDY OF THE PREVALENCE OF MICROALBUMINURIA IN PATIENTS OF ESSENTIAL HYPERTENSION AND ITS CORRELATION WITH THE SEVERITY OF HYPERTENSION AND LEFT VENTRICULAR HYPERTROPHY

Abstract

Objective:To detect the prevalence of microalbuminuria in 100 hypertensive patients and the its
association with LVH(left ventricular hypertrophy) and lipid prole
Methods: we performed a prospective analysis study of 100 patients visiting Balaji medical college and hospital,
Chennai.Inclusion criteria :Hypertensive patients with BP>140/90 mmhg and age more than 30 years.Exclusion
criteria:Patients with renal disease,T2DM,Ischemic heart disease,CVA,pregnancy.microalbuminuria was measured using the
dip stick test ,dened as having UAE in the range of 30-300mg/24h
Results:100 patients were involved in the study fullling the criteria.30 out of 100 patients had microalbuminuria. 21 males out
of 45 were found to have microalbuminuria and 9 out of 25 females were found to have Microalbuminuria.Serum levels of
cholesterol,Triglycerides,and uric acid in patients with microalbuminuria were higher than the levels in those with normal
UAE(urine albumin excretion),and HDL(high density lipid) levels in patients with MA(microalbuminuria)were lower than levels
in patient with normal UAE.On performing ECHO in the study patients ,LVH is noted to be seen in 29 out of 100 patients ,out of
which 22 (73.3%) of the patients had microalbuminuria,and in 71 patients without LVH ,8 had microalbuminuria.Study shows a
high statistical signicant correlation between Microalbuminuria and Left ventricular hypertrophy(p value <0.01).
Conclusion: Hypertension is one of the most common global diseases causing signicant mortality and morbidity.Therefore
proper screening and assessment is required to identify patients at risk. Microalbuminuria is a cause for generalized
atherosclerosis and increased renal endothelial dysfuntion,it positively correlates with the end organ damage such as left
ventricular hypertrophy .Hence it serves as a marker of cardiovascular risk along with other parameters such as BP,lipid prole
and smoking. So, screening for microalbuminuria must be considered to be part of initial work up in every hypertensive patient.