RELATION BETWEEN COMMON CAROTID ARTERY INTIMA MEDIA THICKNESS AND MICROALBUMINURIA IN T2 DM PATIENTS

Dr. Mansa Ram Saran, Dr. Sukh Chain, Dr. Jaya Dadhich

Abstract


Aims and objectives :

To Ascertain the relationship between the temporal occurance of microalbuminuria and common carotid artery-intima media thickness(CCA-IMT)  in patientts with T2DM.

Material and methods :

The study included patients suffering from T2DM (n=20) and age & sex matched control subjects (n=10). Patients and control subjects were examined for intima media thickness by B mode ultrasound. CCA-IMT was calculated 1 cm before bifurcation by the average of the left and the rights CCA-IMT. Microalbuminuria was measured in two overnight sterile urine samples.

Results :

A statistically significant Correlation was observed between microalbuminuria and CCA- IMT in female patients with T2DM and in all patients with T2DM. A statistically significant Cor relation was observed between the duration of DM and microalbuminuria. Also A statistically significent Correlation observed between duration of DM and CCA-IMT.

Conclusion:

There was a statistically significant Correlation was observed between presence of microalbuminuria and CCA-IMT in T2DM patients. In T2DM patientsmicroalbuminuria was associated with increased CCA-IMT.

 


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References


Viberti GC, Keen H. Relevance to pathogenesis and prevention of diabetic nephropathy. Diabetes 1984; 33;686-692.

Schmitz A, Vaeth M. Microalbuminuria: A major risk factor in NIDDM. A 10 Year follow-up study of 503 patients. Diabetic Med 1988; 5:126-134.

Damsgaard EM, Mogensen CE. Microalbuminuria in elderiyhyperglycemic patients and controls. Diabetic Med 1986; 3 : 432-435.


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